Results 91 to 100 of about 193,488 (308)
Dynamics in car ownership: the role of entry into parenthood
This study investigates the impact of entry into parenthood on changes in car ownership. If entry into parenthood affects changes in car ownership, then delay or offset of entry into parenthood might also be an important explanation of recent car travel ...
Abu Toasin Md Oakil +2 more
doaj +1 more source
Parenthood patterns used by parents of psychotic patients [PDF]
Background Most of the psychotic patients have problems in their relationship with their own parents, and often parents begin the impaired relationship.
قمری گیوی, حسین +2 more
core
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Migration and first-time parenthood [PDF]
This article investigates the reproductive behavior of young women and men in the post-Soviet Central Asian republic of Kyrgyzstan, focusing on the link between migration and fertility.
Gunnar Andersson, Lesia Nedoluzhko
core
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Two means two, but must does not mean must:an analysis of recent decisions on the conditions for parental orders in surrogacy [PDF]
This article examines the High Court decisions in Re Z (A Child) (Surrogate Father: Parental Order) [2017] 1 FLR 472 and Re X (A Child) (Parental Order: Time Limit) [2015] 1 FLR 349, which concerned two of the conditions for the granting of ‘parental ...
Brown, Alan
core
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source

