Results 81 to 90 of about 516,834 (295)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A DTI tractography study in pre-readers at risk for dyslexia
Developmental Cognitive Neuroscience, 2015 In adults and school-aged children, phonological aspects of reading seem to be sustained by left dorsal regions, while ventral regions seem to be involved in orthographic word recognition. Yet, given that the brain reorganises during reading acquisition,
Maaike Vandermosten +7 more
doaj +1 more source
The role of parenting styles on behavior problem profiles of adolescents [PDF]
, 2019 Parental behavior is one of the most influential factors on the development of adolescent externalizing and internalizing behavior problems. These behavioral problems are closely related and often co-occur.
Hidalgo García, María Victoria +3 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Support and services for parents : a review of practice development in Scotland [PDF]
, 2007 Three year national evaluated pilot intended to focus on systems and practice for the operation of Parenting ...
Curran, Joe +3 more
core +2 more sources
DEVELOPING COLORING BOOKS TO ENHANCE READING COMPREHENSION COMPETENCE AND CREATIVITY [PDF]
, 2020 Developing a reading learning media can be an effort to increase students’ reading comprehension, but there are many teachers who do not put much attention into it.
., Lisnani, Inharjanto, Anselmus
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
BMC Pregnancy and Childbirth, 2018 Background Becoming the parent of a new baby comes with a range of challenges including difficulties with emotional adjustment, couple relationship issues and difficulty managing common infant behaviors, such as crying and sleep problems.
Mandy Mihelic +2 more
doaj +1 more source
No Place to Grow: The Unsafe and Unstable Housing Conditions of Illinois Pregnant and Parenting Youth and Their Children [PDF]
, 2003 In an attempt to determine the number of pregnant and parenting youth in need of alternative living arrangements throughout Illinois, the Center for Impact Research (CIR), in collaboration with its working group members, conducted a statewide needs ...
Helene M. Marcy
core
Socioeconomic risk, parenting during the preschool years and child health age 6 years [PDF]
, 2006 Parent–child relationships and parenting processes are emerging as potential life course determinants of health. Parenting is socially patterned and could be one of the factors responsible for the negative effects of social inequalities on health, both
B. Bell +18 more
core +1 more source