Results 81 to 90 of about 2,046,882 (412)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Parental involvement to parental engagement: a continuum [PDF]

Educational Review, 2013
Based on the literature of the field, this article traces a continuum between parental involvement with schools, and parental engagement with children’s learning. The article seeks to shed light on an area of confusion; previous research has shown that different stakeholder groups understand “parental engagement” in different ways.
Goodall, Janet, Montgomery, Caroline
openaire   +3 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

The effect and cost-effectiveness of a group-based parenting intervention for parents of preschool children with subclinical neurodevelopmental disorders and mental health problems: protocol for a multiple-baseline single-case experimental design (SCED) with a pre-, post and follow-up

BMC Psychology
Background Young children with subclinical neurodevelopmental disorders (NDDs) and concurrent emotional and behavioral problems (EBP) are at significant risk of negative short- and long-term outcomes.
Anton Dahlberg, Vedrana Bolic Baric, Filipa Sampaio, Karin Fängström   +3 more
doaj   +1 more source

Let's not throw out the baby with the bathwater: applying the principle of ‘universalism without uniformity' to autonomy-supportive and controlling parenting [PDF]

, 2015
Socialization scholars differ in how they view parenting processes: On one hand, scholars working from the perspective of the Self-Determination Theory (SDT) underscore the universally growth-promoting role of parenting that is perceived to support ...
Soenens, Bart, Van Petegem, Stijn, Vansteenkiste, Maarten   +2 more
core   +1 more source

Parental Style, Dating Violence and Gender [PDF]

, 2019
The relationship between parenting styles and teen dating violence has become a relevant research topic in recent years, especially related to violence inflicted online. To more fully understand this relationship, the objective of the present study was
Muñiz Rivas, María, Povedano Díaz, Amapola, Vera Perea, María   +2 more
core   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Parent Mindfulness, Parenting, and Child Psychopathology in China

Mindfulness, 2019
ObjectivesConsidering the Western-Eastern cultural differences in parenting practices, as well as the relative paucity of research on the use of mindfulness-based programs by Chinese parents, we replicated a recently proposed Western model of mindfulness.
Z. Han, Nigela Ahemaitijiang, J. Yan, Xiaoyi Hu, J. Parent, Chelsea F. Dale, Karissa DiMarzio, Nirbhay N. Singh   +7 more
semanticscholar   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source