Results 71 to 80 of about 5,810,137 (395)

Parents Anonymous Outcome Evaluation: Promising Findings for Child Maltreatment Reduction [PDF]

, 2008
Parents Anonymous(R) mutual support groups for parents are aimed at strengthening families and reducing child maltreatment. NCCD performed a national evaluation to assess whether parent participation in Parents Anonymous(R) was associated with change in ...

core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Testing the Moderating Role of Social Context on Media Violence Effect in the Case of Peer Aggression among Adolescents [PDF]

Studia Psychologica, 2017
The main aim of the study was to examine a potential moderator role of social context in which children are exposed to media (alone, with peers, with parents) in the relationship between the frequency of media use and the frequency of committed peer ...
Tena Velki, Gordana Kuterovac Jagodić
doaj   +1 more source

Parental involvement to parental engagement: a continuum [PDF]

Educational Review, 2013
Based on the literature of the field, this article traces a continuum between parental involvement with schools, and parental engagement with children’s learning. The article seeks to shed light on an area of confusion; previous research has shown that different stakeholder groups understand “parental engagement” in different ways.
Goodall, Janet, Montgomery, Caroline
openaire   +3 more sources

'Heaven starts at your parents' feet' : adolescent bowing to parents and associated spiritual attitudes [PDF]

, 2010
In a quantitative survey of religious attitudes and practices in a multi-religious sample of 369 school pupils aged between 13 and 15 in London, the practice of bowing to parents was found widespread in 22% of adolescents spanning several religious ...
Deleuze G., Francis L.J., Ganeri A., Gates B., Harvey P., Hirsch A., Hong S., Hurvitz A., Jackson R., Kay W.K., Kay W.K., Lewis J.M., Min P.G., Nesbitt E., Phra Nicholas Thanissaro, Sure H., Valdes G., Xing G., Young A.   +18 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

VIEWS OF FOSTERCHILDREN ABOUT CONTACTS WITH PARENTS AND RELATIVES

Human Research in Rehabilitation, 2016
This paper presents the results of research on the views of children about contacts with their birth parents and relatives. The views of children are seen through their experience in contacts and the wishes of children that relate to future contacts ...
Ljiljana Skrobić
doaj  

Parents' beliefs and knowledge about the management of acute otitis media: A qualitative study [PDF]

, 2015
BACKGROUND: Acute otitis media is a common reason for antibiotic prescribing, despite strong evidence that antibiotics provide minimal benefit. Studies have demonstrated that patients’ (or parents’) expectations of antibiotics often influence general ...
Del Mar, Chris, Hansen, Malene Plejdrup, Hoffmann, Tammy C., Howlett, Janine   +3 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source