Results 81 to 90 of about 890,254 (268)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Impact of class cancellations on parents’ and children’ adaptation following an outbreak of the Omicron variant during the COVID-19 pandemic in Taiwan in April 2022

open access: yesBMC Public Health
Objective To explore the impact on Taiwanese parents and children following an outbreak of the Omicron variant during the COVID-19 pandemic. Methods Data were collected following class cancellations mandated by the Ministry of Education due to an ...
Kuo-Yu Chao   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Roy’s Adaptation Model and the Dual Process Model of Grieving substantiating palliative nursing care to the family

open access: yesO Mundo da Saúde, 2017
One of the principles of palliative care is to assist in identifying and mobilizing a support system to help the family deal with the patient’s illness and his or her own grief. In this perspective, the objective of this study was to propose a reflection
Vladimir Araujo da Silva   +3 more
doaj  

PARENTING STYLES, POSITIVE PARENTING AND PARENTS FORMATION

open access: yes, 2013
El presente trabajo surge como una inquietud de los autores, (integrantes de una ONG que se dedica al trabajo con niños y adolescentes que han sufrido la vulneración de algunos de sus derechos) por revisar en un rápido recorrido los desarrollos conceptuales que nos parecen más relevantes sobre los estilos educativos parentales y las posibles ...
Capano, Álvaro, Ubach, Andrea
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

An intervention for fear of progression in childhood cancer patients and their parents: feasibility and preliminary efficacy in a pilot randomised controlled trial

open access: yesBMC Pediatrics
Background Fear of progression (FoP) is a significant psychosocial burden for children with cancer and their parents, influencing their quality of life (HRQoL) and emotional adjustment.
Jessy Herrmann   +9 more
doaj   +1 more source

An app-based training for adolescents with problematic digital-media use and their parents (Res@t digital): protocol for a cluster-randomized clinical trial

open access: yesFrontiers in Psychiatry
BackgroundDigital media-use disorders (DMUD) in adolescents are a rising phenomenon associated with psychological distress, comorbid mental disorders, and high burden on affected families.
Kerstin Paschke   +13 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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