Results 101 to 110 of about 1,955,160 (307)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Freshman Orientation Parents' Tea
, 1974 Parents' tea at Freshman orientation, Teaneck ...
unknown
core
Pragmatics and Parenting [PDF]
Journal of Pediatric Nursing, 2018 Pragmatic Children's Nursing Theory draws on the theory principles of North American Pragmatist including the work of William James, Richard Rorty, and John Dewy and incorporates Margaret Urban Walkers' work on expressive collaborative feminism.In this discussion paper I explore how the role of parents is framed in Pragmatic Children's Nursing Theory ...
openaire +3 more sources
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Engaging Indigenous parents in their children’s education [PDF]
, 2014 This resource sheet identifies some of the key practices that have underpinned programs or practices for schools and early learning environments that have successfully engaged Indigenous parents with their children’s education.
Daryl Higgins, Sam Morley
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Adoption handbook and directory of adoption related services. [PDF]
, 1995 The Adoptive Parents Association of Ireland would like to thank all the people who, with the.help reassurance and which make this handbook possible. There was much encouragement from the many social workers contacted for information and great help ...
Adoptive Parents Association of Ireland
core
Acta Obstetricia et Gynecologica ScandinavicaIntroduction Numerous studies have shown that the diagnostic performance and reproducibility of visual recognition of endometriosis during laparoscopy are poor.
Antoine Netter +7 more
doaj +1 more source