Results 211 to 220 of about 47,390 (286)
ABSTRACT This case report describes the successful surgical management of a chronic subdural hematoma (CSDH) in a 45‐year‐old male with severe aplastic anemia (AA) and severe thrombocytopenia. The patient presented with worsening headaches, and imaging confirmed a progressive CSDH with midline shift. Despite a platelet count of 22 × 109/L, preoperative
Zhenghao Fu, Jiankan Lu, Xinqing Deng
wiley +1 more source
ABSTRACT Background Cutaneous adnexal carcinomas are a very rare group of cancers arising from appendageal structures of the skin. More than half occur in the head and neck region. No standard treatments exist for metastatic disease. Methods A 48‐year‐old postmenopausal female presented with an enlarging scalp lesion.
Nilesh Kapoor +3 more
wiley +1 more source
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang +5 more
wiley +1 more source
Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva +5 more
wiley +1 more source
Effects of Volumetric Alterations of the Tongue Base on Craniofacial Growth in the Adult Minipig
Craniofacial growth is a continuous process that constantly adapts to environmental, physiological, and genetic factors. All of these factors induce alterations in soft tissues that directly impact the size and rate of growth of skeletal structures. In the present study, two conditions of volume alterations of the tongue base were induced in a Yucatán ...
Amylia Liu +3 more
wiley +1 more source
Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu +8 more
wiley +1 more source
A new in silico model to precisely design focused ultrasound brain therapies
Abstract Background Focused ultrasound (FUS) combined with microbubbles enables transient and noninvasive blood–brain barrier (BBB) opening, facilitating targeted drug delivery. However, accurate treatment planning remains difficult due to inter‐patient anatomical variability and the common assumption in simulations that brain tissues behave like water.
Allegra Conti +4 more
wiley +1 more source
Osteoradionecrosis of the Scalp: A Case Series Highlighting Clinical Challenges and Literature Gaps
Abstract Objective Cutaneous carcinoma of the scalp is a common, but underreported, and complications of scalp irradiation remain poorly described. Many patients receive primary or postoperative radiation to the scalp, and complications from treatment are not well described.
Claire M. E. Gleadhill +5 more
wiley +1 more source

