Results 31 to 40 of about 847,688 (227)
Potchefstroom Electronic Law JournalGlobal climate change mitigation within the framework of the 2015 Paris Agreement on Climate Change essentially revolves around a hybrid of bottom up and top-down state action.
Vieviene Antifon
doaj +1 more source
, 2000 The results of experiments on atmospheric neutrinos are summarized, with the important exception of Superkamiokande. The main emphasis is given to the Soudan-2 and MACRO experiments.
Abrosio +50 more
core +2 more sources
Paris Climate Agreement passes the cost-benefit test
Nature Communications, 2020 Relative economic benefits of achieving temperature targets have not properly accounted for damages at higher temperatures. Here the authors integrate dynamic cost-benefit analysis with a damage-cost curve and show that the Paris Climate Agreement ...
Nicole Glanemann +2 more
doaj +1 more source
Earth System Governance, 2021 This article aims to analyse the potential for international climate governance to promote the decarbonisation of land transport. It first summarises challenges and barriers that impede the transformation of the sector.
Wolfgang Obergassel +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Staying on Track from Paris: Advancing the Key Elements of the Paris Agreement [PDF]
, 2016 The Paris Agreement adopted in December 2015 provides essential building blocks for universal action to address climate change. Now, much work is needed to breathe life into the provisions and commitments of the Agreement in order to realize the globally
Cynthia Elliott +8 more
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Non-state actors in hybrid global climate governance: justice, legitimacy, and effectiveness in a post-Paris era [PDF]
, 2017 In this article, we outline the multifaceted roles played by non-state actors within the United Nations Framework Convention on Climate Change and place this within the wider landscape of global climate governance.
Kuyper, Jonathan W. +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source