Results 91 to 100 of about 2,049,123 (312)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Appalachian National Park: Synopsis of work accomplished

open access: yes, 2015
This 32-page booklet is titled, “Appalachian National Park: Synopsis of work accomplished” since the founding of the Appalachian National Park Association.
Ambler, Chase P., 1865-1932;
core  

Ridgefield Park Environmental Resource Inventory Addendum I: Water Sampling Results

open access: yes, 2000
This addendum is a summary of results for the 2000-2001 school year of water sampling performed by staff and students of the Ridgefield Park school system. Test types and results are listed in table form.Prepared for the Village of Ridgefield Park with a

core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Map of Great Smoky Mountains National Park

open access: yes, 2015
Today’s Great Smoky Mountains National Park encompasses over 500,000 acres, almost evenly divided between North Carolina and Tennessee. This contemporary 2014 map was produced and distributed by the National Park Services as part of a brochure promoting
United States. National Park Service
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

MATERIALS FOR THE INSECT FAUNA OF THE SYRDARYA-TURKESTAN STATE REGIONAL NATURAL PARK [PDF]

open access: yesVestnik Issyk-Kulʹskogo universiteta
The scientific article considers materials based on the insect fauna of the Syrdarya no-Turkestan State Regional Natural Park. Syrdarya-Turkestan State Regional Natural Park is a specially protected natural area of local importance with the status of a ...
Yesenbekova P. A.   +2 more
doaj   +1 more source

Park dedication: notice

open access: yes, 2015
This document, written in the summer of 1940, expresses the interest on behalf of President Franklin D. Roosevelt to be on hand to dedicate the Great Smoky Mountains National Park. The dedication did take place that year, on Labor Day, September 2, 1940.
United States. National Park Service;
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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