Results 141 to 150 of about 2,419,951 (303)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Memorandum to Appalachian National Park Association membership

open access: yes, 2015
This 3-page memorandum was written in September 1901 by Appalachian National Park Association president George S. Powell (b. 1848). Powell includes a summary of the association’s accomplishments to date as well as a quote by Senator Pritchard advocating ...
Powell, George S.;
core  

Child safety in parks' playgrounds (a case study in Tehran’s sub-district parks)

open access: yesSalāmat-i kār-i Īrān, 2010
Background and aimsSafety is a complex concept and multidisciplinary science which is included some difference areas from industrial sectors to urban public arenas.
A.H. Mirlouhi Falavarjani   +3 more
doaj  

PARKING AND PARKING OF MOTOR VEHICLES

open access: yes
The rapid urbanization and increasing number of motor vehicles have led to significant challenges related to parking management in urban areas. This article explores the various aspects of parking and parking management, including types of parking, design considerations, the impact of parking on traffic congestion, and innovative solutions to parking ...
openaire   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Editorials commenting on the Appalachian National Park movement

open access: yes, 2015
This undated, typewritten 20-page document lists various favorable comments made about the Appalachian National Park Association by newspapers and individuals from all over the country.
Ambler, Chase P., 1865-1932;
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Stickers: Push the Appalachian National Park

open access: yes, 2015
The Appalachian National Park Association carried out a wide-ranging promotional campaign throughout the eastern U.S. Within the first few months of its operation, the Association printed these colorful stickers with the motto, “Push the Appalachian ...
Appalachian National Park Association;
core  

Letterhead, Appalachian National Park Association

open access: yes, 2015
The letterhead for the Appalachian National Park Association lists the officers and committees of the organization, beginning in 1899. At the very first meeting of the association, George Powell was elected president and Chase Ambler was named secretary ...

core   +1 more source

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