Results 141 to 150 of about 2,049,123 (312)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Park fiction - a participatory artistic park project

open access: yes, 2014
The extraordinary green recreational area Park Fiction was proposed, planned, and established by a group of artists, residents, and local institutions in Hamburg from 1994 until 2005.
Rühse, Viola
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

PARKING AND PARKING OF MOTOR VEHICLES

open access: yes
The rapid urbanization and increasing number of motor vehicles have led to significant challenges related to parking management in urban areas. This article explores the various aspects of parking and parking management, including types of parking, design considerations, the impact of parking on traffic congestion, and innovative solutions to parking ...
openaire   +2 more sources

Aerial view of the Park City Ski Area.

open access: yes, 1996
Aerial view of Park City and the ski runs on the mountain at Park City Mountain Resort, photo taken between 1996 and ...
Park City Ski Corp. / Lori Adamski Peek
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Child safety in parks' playgrounds (a case study in Tehran’s sub-district parks)

open access: yesSalāmat-i kār-i Īrān, 2010
Background and aimsSafety is a complex concept and multidisciplinary science which is included some difference areas from industrial sectors to urban public arenas.
A.H. Mirlouhi Falavarjani   +3 more
doaj  

General information regarding Yellowstone National Park.

open access: yes, 1912
Mode of access: Internet.Published by the Department of the Interior, 1912- (National Park Service, 1917-
United States. National Park Service.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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