Results 111 to 120 of about 1,650,645 (209)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Afet Sonrası Bir Kriz Yönetimi Bileşeni Olarak Kent Parkları; Malatya Örneği
Düzce University Faculty of Forestry Journal of ForestryAfetler sonucu doğal ve kültürel kaynakların süratle tükendiği günümüzde afet sonrası organizasyon çözümlemeleri önem taşıyan bir unsur haline gelmiştir. Bu noktada 6 Şubat depreminden etkilenen illerden biri olan Malatya ilinde belirlenen beş açık yeşil
Emine Deniz +2 more
doaj +1 more source
Reasons in Favor of the Establishment of a National Park
, 2015 These three editions of the same brochure were written and distributed by the Appalachian National Park Association. The booklets list multiple reasons to support the “establishment of a national park in the mountains of western North Carolina.” Printed ...
Appalachian National Park Association;
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2015 This document, written in the summer of 1940, expresses the interest on behalf of President Franklin D. Roosevelt to be on hand to dedicate the Great Smoky Mountains National Park. The dedication did take place that year, on Labor Day, September 2, 1940.
United States. National Park Service;
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Appalachian National Park Association Newspaper Clippings, 1902-1907, 1925, 1928
, 2015 This is one of two notebooks assembled by the Appalachian National Park Association that includes documents and news clipping about the organization. The Appalachian National Park Association was formed in 1899 for the purpose of promoting the idea of a ...
Appalachian National Park Association;
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Requisition: Appalachian National Park Association
, 2015 This is a blank copy of a requisition form for ordering on behalf of the Appalachian National Park Association.Requisition No. On REQUISITION. No — Appalachian National Park Association* \ AH orders for printing or other supplies must be accompanied by
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source