Results 71 to 80 of about 2,416,181 (303)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Park dedication: correspondence
, 2015 This letter provides instructions to deal with parking during the dedication of the Great Smoky Mountains National Park. The dedication took place on Labor Day, September 2, 1940.
Eakin, J. Ross, 1879-1946
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I parchi, strumenti moderni per la gestione integrata del territorio
Ri-vista: Ricerche per la Progettazione del Paesaggio, 2015 The “peculiarity” of the park: Gambino research for the interpretation of the international framework and its comparison with the Italian background. Theoretical and practical contributions on critical issues of the national context: the Protected Area ...
Giampiero Sammuri
doaj +1 more source
Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah +5 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
North Carolina Park Commission: "Options"
, 2016 This ledger is part of the records of the North Carolina Park Commission. Oddly, the book is labeled, “Options.” The ledger includes various tracts of land to be acquired for the Great Smoky Mountains National Park.
North Carolina Park Commission;
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Dal parco al progetto di territorio: evoluzione o discontinuità?
Ri-vista: Ricerche per la Progettazione del Paesaggio, 2015 In celebrating Roberto Gambino, I underline the ethical role of his professional activity, systematically oriented to experiment scientific advancements of town planning towards territorial and landscape quality in fostering public interest.
Alberto Magnaghi
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Park dedication: press release
, 2015 This press release from the Department of the Interior and the National Park Service announces the events planned for the dedication of the Great Smoky Mountains National Park on Labor Day, September 2, 1940.
United States. Department of the Interior;
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source