Results 71 to 80 of about 972,474 (267)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EnergiesTo improve the regulatory capacity of distributed resources within the park and enhance the flexibility of market transactions, this paper introduces a distributed dispatch and profit allocation method grounded in cooperative game theory and the ...
Hanwen Wang +3 more
doaj +1 more source
Parki in njihovi uporabniki [PDF]
Urbani Izziv, 2008 Prispevek obravnava rabo mestnih parkov. Tematiko o uporabniško-prostorskih odnosih kritično osvetli z dveh vidikov: dejanskih razmerij v konkretnih okoljih, pridobljenih na podlagi podatkov z več zaporednimi opazovanji in s kartiranjem vedenj ter s ...
Barbara Goličnik
doaj
European Journal of Entomology, 2014 In this study, we investigate the changes in both vascular plant and carabid beetle assemblages in response to reducing the intensity of management of park lawns in the city of Helsinki.
Stephen VENN, D. KOTZE
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Parking to parks : rethinking parking lot system in Shenzhen
, 2015 published_or_final_version ; Architecture ; Master ; Master of Landscape ...
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The first open public space in Krasnoyarsk
Проект Байкал, 2021 Krasnoyarsk parks are studied in the general system of green areas of the city. The Central Park of Krasnoyarsk is analyzed in detail, its evolution is traced through its periods.
Olga Blyankinshtein, Natalya Popkova
doaj