How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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By-laws of the Appalachian National Park Association
This item includes two drafts of a 5-page document that outlines the by-laws of the Appalachian National Park Association. The original by-laws proposed that the organization be named the “Southern National Park Association” but, by the time it was ...
Gilmer, Robert D., 1858-1925; Lawrence, Thomas; Wittkowsky, Samuel, 1835-1911; Hays, J. F.; Gwyn, Walter B., 1853-1911;
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Mitigating Effects of Nest Structure on Predation Risk in Hainan Partridge (<i>Arborophila ardens</i>). [PDF]
Zhang Y +6 more
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
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Exterior of the New Park Hotel; front facade of 3-story brick building at 573 Main St. viewed from slightly downhill, looking southwest. Fence at right with a few houses on Park Ave. & Woodside behind.
Jenkins, J.E.
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Willamalane Park & Recreation District : Lively Park master plan
38 pp. Includes maps. Adopted September 28, 2005. Captured March 20, 2007.The Lively Park Master Plan identifies and documents the long-term, desired development of Jack B. Lively Memorial Park (Lively Park), home of Splash!
Willamalane Park and Recreation District
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Over-hydration as a key modifiable predictor of obstructive sleep apnea severity in dialysis patients with daytime sleepiness. [PDF]
Park S +6 more
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
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Erratum to "Interleukin-1β Signaling Contributes to Cell Cycle Arrest and Apoptotic Cell Death by Leptin via Modulation of AKT and p38MAPK in Hepatocytes" [Biomol Ther 32(5), 611-626 (2024)]. [PDF]
Baral A, Park PH.
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

