Results 141 to 150 of about 2,416,181 (303)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Memorandum to Appalachian National Park Association membership
, 2015 This 3-page memorandum was written in September 1901 by Appalachian National Park Association president George S. Powell (b. 1848). Powell includes a summary of the association’s accomplishments to date as well as a quote by Senator Pritchard advocating ...
Powell, George S.;
core
Child safety in parks' playgrounds (a case study in Tehran’s sub-district parks)
Salāmat-i kār-i Īrān, 2010 Background and aimsSafety is a complex concept and multidisciplinary science which is included some difference areas from industrial sectors to urban public arenas.
A.H. Mirlouhi Falavarjani +3 more
doaj
PARKING AND PARKING OF MOTOR VEHICLES
The rapid urbanization and increasing number of motor vehicles have led to significant challenges related to parking management in urban areas. This article explores the various aspects of parking and parking management, including types of parking, design considerations, the impact of parking on traffic congestion, and innovative solutions to parking ...
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Editorials commenting on the Appalachian National Park movement
, 2015 This undated, typewritten 20-page document lists various favorable comments made about the Appalachian National Park Association by newspapers and individuals from all over the country.
Ambler, Chase P., 1865-1932;
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Stickers: Push the Appalachian National Park
, 2015 The Appalachian National Park Association carried out a wide-ranging promotional campaign throughout the eastern U.S. Within the first few months of its operation, the Association printed these colorful stickers with the motto, “Push the Appalachian ...
Appalachian National Park Association;
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Letterhead, Appalachian National Park Association
, 2015 The letterhead for the Appalachian National Park Association lists the officers and committees of the organization, beginning in 1899. At the very first meeting of the association, George Powell was elected president and Chase Ambler was named secretary ...
core +1 more source