Results 111 to 120 of about 2,416,181 (303)

Great Smoky Mountains and the National Park

open access: yes, 2016
This article “The Great Smoky Mountains and the National Park” was written by Horace Kephart and looks to have been reprinted by the National Park Service.
Kephart, Horace, 1862-1931;
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Ridgefield Park Environmental Resource Inventory Addendum I: Water Sampling Results

open access: yes, 2000
This addendum is a summary of results for the 2000-2001 school year of water sampling performed by staff and students of the Ridgefield Park school system. Test types and results are listed in table form.Prepared for the Village of Ridgefield Park with a

core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Park dedication: traffic control

open access: yes, 2015
This confidential memorandum provides instructions to deal with traffic during the dedication of the Great Smoky Mountains National Park. The dedication took place on Labor Day, September 2, 1940.
Eakin, J. Ross, 1879-1946
core  

Parking in the City

open access: yesActa Physica Polonica A, 2007
We show that the spacing distribution between parked cars can be obtained as a solution of certain linear distributional fixed point equation. The results are compared with the data measured on the streets of Hradec Kralove. We also discuss a relation of this results to the random matrix theory.
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Editorial: Appalachian National Park

open access: yes, 2015
In promoting a national park in the southern Appalachians, Chase Ambler wrote dozens of editorials and submitted them to newspapers and magazines throughout the east coast.
Ambler, Chase P., 1865-1932;
core  

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