The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Response to "Methodological Challenges in Associating T2-Weighted Imaging Features in Breast Cancer With Clinical and Pathologic Findings". [PDF]
Park VY, Youn I, Roh YH.
europepmc +1 more source
Urban park use and children's physical activity in Minneapolis-Saint Paul Minnesota: Parks and Recreation for Kids Study (PARKS). [PDF]
French SA +6 more
europepmc +1 more source
Bioprocess Development of a Human Monoclonal Antibody against MERS-CoV: Analytical and Preclinical Studies. [PDF]
Lim J +13 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Association of hemoglobin levels with metabolic syndrome and its components in older korean males: A nationwide population-based cross-sectional study. [PDF]
Park JM.
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Correction to: Whole Genome Sequencing in 25 Families with Suspected Inborn Errors of Immunity: Diagnostic Yield and Clinical Relevance of Genome-wide Analysis. [PDF]
Lee JK +8 more
europepmc +1 more source
Associations of park visits, physical activity and health outcomes among churchgoing Latino adults in low-income urban communities. [PDF]
Derose KP +6 more
europepmc +1 more source

