Results 71 to 80 of about 2,802,612 (287)

How driver behaviour and parking alignment affects inductive charging systems for electric vehicles [PDF]

open access: yes, 2015
Inductive charging, a form of wireless charging, uses an electromagnetic field to transfer energy between two objects. This emerging technology offers an alternative solution to users having to physically plug in their electric vehicle (EV) to charge ...
Wilson, Daniel   +6 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Regulating on-street parking [PDF]

open access: yes
Consider the choices available to a shopper driving to a city and trying to park downtown. One option, typical to many cities, is to follow the signposts to an off-street parking facility, which is often privately operated.
Edward Calthrop, Stef Proost
core   +2 more sources

ParkSense: A Smartphone Based Sensing System For On-Street Parking [PDF]

open access: yes, 2013
Studies of automotive traffic have shown that on average 30% of traffic in congested urban areas is due to cruising drivers looking for parking. While we have witnessed a push towards sensing technologies to monitor real-time parking availability ...
Nawaz, Sarfraz   +2 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Evaluation of Parking Lots in Terms of Plant Preferences and Planting Design Criteria; The Case of Akdeniz University Campus

open access: yesJournal of Architectural Sciences and Applications, 2021
The aim of this study is to evaluate the parking lots in Akdeniz University campus within the scope of plant material diversity, planting design elements and criteria.
Ceren Selim
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Accident Diagnosis and Evaluation System in Parking Lots Using Multisource Data Based on Bayesian Networks

open access: yesJournal of Advanced Transportation, 2023
Parking lots have many complex structures, diverse functions, and plentiful elements. The frequent flow of vehicles with narrow and dim spaces increases the probability of various traffic accidents.
Yijing Zhang   +5 more
doaj   +1 more source

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