Results 181 to 190 of about 240,114 (259)

Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Although dopamine transporter (DaT) imaging is a valuable diagnostic biomarker, few studies have investigated its utility in objectively monitoring disease progression in patients with Parkinson's disease (PD). To date, no study has established a longitudinal relationship between the DaT signal decline and the motor symptom increase ...
Verena Dzialas, Gérard N. Bischof, Kathrin Möllenhoff, Alexander Drzezga, Thilo van Eimeren   +4 more
wiley   +1 more source

NOX2 in Alzheimer's and Parkinson's disease. [PDF]

Redox Biol
Dustin CM, Shiva SS, Vazquez A, Saeed A, Pascoal T, Cifuentes-Pagano E, Pagano PJ.   +6 more
europepmc   +1 more source

AI in Neurology: Everything, Everywhere, all at Once PART 2: Speech, Sentience, Scruples, and Service

Annals of Neurology, EarlyView.
Artificial intelligence (AI) applications are finding use in real‐world neurological settings. Whereas part 1 of this 3‐part review series focused on the birth of AI and its foundational principles, this part 2 review shifts gears to explore more practical aspects of neurological care.
Matthew Rizzo
wiley   +1 more source

α-Synuclein in Parkinson's Disease: From Bench to Bedside. [PDF]

Med Res Rev
Bellini G, D'Antongiovanni V, Palermo G, Antonioli L, Fornai M, Ceravolo R, Bernardini N, Derkinderen P, Pellegrini C.   +8 more
europepmc   +1 more source

AI in Neurology: Everything, Everywhere, All at Once Part 3: Surveillance, Synthesis, Simulation, and Systems

Annals of Neurology, EarlyView.
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley   +1 more source

Suicidal ideation after subthalamic stimulation in Parkinson's Disease: A critical concern. [PDF]

Brain Spine
Alex GS, Popoola OI, Okon II.
europepmc   +1 more source

Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland, Sygrid van der Zee, Giulia Carli, Anne C. Slomp, Emile d'Angremont, Jeffrey M. Boertien, Teus van Laar   +6 more
wiley   +1 more source

Predicting dementia in people with Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Aborageh M, Hähnel T, Martins Conde P, Klucken J, Fröhlich H.   +4 more
europepmc   +1 more source

Elevated α‐Synuclein Aggregate Levels in the Urine of Patients with Isolated REM Sleep Behavior Disorder and Parkinson's Disease

Annals of Neurology, EarlyView.
Parkinson's disease (PD) is a neurodegenerative disorder characterized by α‐synuclein aggregation in neurons. Recent advances suggest α‐synuclein aggregates could serve as a biomarker for PD and related synucleinopathies. This study used surface‐based fluorescence intensity distribution analysis (sFIDA) to measure α‐synuclein aggregates in urine ...
Laura Müller, Pelin Özdüzenciler, Charlotte Schedlich‐Teufer, Aline Seger, Hannah Jergas, Gereon R. Fink, Dieter Willbold, Michael Sommerauer, Michael T. Barbe, Gültekin Tamgüney   +9 more
wiley   +1 more source