Results 181 to 190 of about 9,647,508 (315)

CRISPRa Lipid Nanocomplex‐Mediated Mt3 Targeting Enhances Astrocytic Endocytosis of Amyloid‐β in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
GeTe exhibits intrinsically high carrier concentrations that limit its thermoelectric performance. Herein, CuAgSe alloying synergistically tunes the band structure, induces band flattening and valence‐band convergence, promotes Cu‐ion delocalization, and generates multiscale hierarchical structures to suppress phonon transport.
Junhang Park, Boyoung Kim, Minki Ha, Moonsu Park, Hongji Ryu, Hyerin Yu, Sungsoo Park, Yoon‐Seok Roh, Key‐Hwan Lim, Jin Tae Hong, Sang‐Bae Han, Chun‐Woong Park, Seok‐Beom Yong, Hanseul Park   +13 more
wiley   +1 more source

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease.

New England Journal of Medicine, 2003
P. Krack, A. Batir, N. Van Blercom, S. Chabardès, V. Fraix, C. Ardouin, A. Koudsié, P. Limousin, A. Benazzouz, J. Lebas, A. Benabid, P. Pollak   +11 more
semanticscholar   +1 more source

Cardiac 123I-MIBG uptake in de novo Brazilian patients with Parkinson's disease without clinically defined dysautonomia [PDF]

, 2014
Marco Antônio Araújo Leite, Osvaldo J. M. Nascimento, João Santos Pereira, Clayton Amaral, Cláudio Tinoco Mesquita, Jader Cunha de Azevedo, Adriana Soares Xavier de Brito, Felipe Villela Pedras   +7 more
openalex   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

Cell, 2016
T. Sampson, Justine W. Debelius, Taren M. Thron, Stefan Janssen, Gauri G. Shastri, Z. Ilhan, Collin Challis, Catherine E. Schretter, S. Rocha, V. Gradinaru, M. Chesselet, A. Keshavarzian, K. Shannon, R. Krajmalnik-Brown, P. Wittung-Stafshede, R. Knight, S. Mazmanian   +16 more
semanticscholar   +1 more source

Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid

Advanced Science, EarlyView.
α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė, Darius Šulskis, Arūnė Jocytė, Urtė Venclovaitė, Rimgailė Tamulytė, Mantas Žiaunys, Vytautas Smirnovas, Andrius Sakalauskas   +7 more
wiley   +1 more source

A Prediction Model for Depression in Patients with Parkinson's Disease [PDF]

, 2013
Eun Sook Bae, Sang Myung Chun, Jae Woo Kim, Chang Wan Kang   +3 more
openalex   +1 more source

Evaluation of type 1 diabetes mellitus as a risk factor of Parkinson's disease in a Drosophila model [PDF]

, 2023
F. Sanz, Guillermo Martínez‐Carrión, Cristina Solana‐Manrique, Nuria Paricio   +3 more
openalex   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Parkinson's disease and reading performance. [PDF]

Ophthalmic Physiol Opt
Herrero-Gracia A, Hernández-Andrés R, Merino CV, Muedra CP, Ciuffreda KJ, Díez-Ajenjo MA.   +5 more
europepmc   +1 more source