Results 181 to 190 of about 9,423,446 (404)

RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes

Neurobiology of Disease, 2019
Non-neuronal cell types such as astrocytes can contribute to Parkinson's disease (PD) pathology. The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) is one of the most common known causes of familial PD.
Heather D.E. Booth, Frank Wessely, Natalie Connor-Robson, Federica Rinaldi, Jane Vowles, Cathy Browne, Samuel G. Evetts, Michele T. Hu, Sally A. Cowley, Caleb Webber, Richard Wade-Martins   +10 more
doaj  

Satisfaction, effectiveness, and usability of telerehabilitation for Parkinson's disease patients

Journal of Rehabilitation Medicine
Objective: To evaluate the satisfaction, effectiveness, and usability of a telerehabilitation programme for Parkinson’s disease (PD) patients. Design: Prospective cohort study.
Shohei Okusa, Hiroki Saegusa, Kazuya Miyakawa, Yuta Tsutsumi, Sae Ishida, Kyoko Nishikata, Tomonori Nukariya, Toshiki Tezuka, Yoshihiro Nihei, Yasuhiro Kitagawa, Shin-ichiro Kubo, Norihiro Suzuki, Jin Nakahara, Morinobu Seki   +13 more
doaj   +1 more source

Bromocriptine alone or associated with L-dopa plus benserazide in Parkinson's disease. [PDF]

, 1977
T. Caraceni, I. Celano, Eugenio Parati, F. Girotti   +3 more
openalex   +1 more source

Oscillation-specific nodal alterations in early to middle stages Parkinsons disease. [PDF]

, 2019
Background: Different oscillations of brain networks could carry different dimensions of brain integration. We aimed to investigate oscillation-specific nodal alterations in patients with Parkinsons disease (PD) across early stage to middle stage by ...
Gu, Quanquan, Guan, Xiaojun, Guo, Tao, Huang, Peiyu, Liu, Chunlei, Pu, Jiali, Wang, Jiaqiu, Wei, Hongjiang, Xu, Xiaojun, Xuan, Min, Zeng, Qiaoling, Zhang, Baorong, Zhang, Min-Ming, Zhang, Yuyao, Zhou, Cheng   +14 more
core  

Parkinson's Disease Mechanisms and Models

Neuron, 2003
W. Dauer, S. Przedborski
semanticscholar   +1 more source

3D Printing for Neural Repair: Bridging the Gap in Regenerative Medicine

Advanced Materials, EarlyView.
This perspective article discusses how 3D bioprinting is advancing the development of neural tissue models and implants. It highlights recent progress in fabricating complex, multicellular neural constructs, examines current technical barriers, and outlines future applications in disease modeling, neurotoxicity testing, and regenerative therapies ...
Mitchell St Clair‐Glover, Zhilian Yue, Mirella Dottori   +2 more
wiley   +1 more source

Use of botulinum toxin in the management of dystonia in Parkinson’s disease

Frontiers in Neuroscience
Botulinum toxin is one of the most potent neurotoxins, but when injected into an overactive muscle, it can transiently alleviate an involuntary movement, such as dystonia.
Charenya Anandan, Charenya Anandan, Joseph Jankovic   +2 more
doaj   +1 more source

Muscle silent period in Parkinson's disease [PDF]

, 1971
Don C. Higgins, N. H. Haidri, Asa J. Wilbourn   +2 more
openalex   +1 more source

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1

Science, 2004
E. Valente, P. Abou-Sleiman, V. Caputo, M. Muqit, K. Harvey, S. Gispert, Zeeshan Ali, D. Del Turco, A. Bentivoglio, D. Healy, A. Albanese, R. Nussbaum, R. González-Maldonado, T. Deller, S. Salvi, P. Cortelli, W. Gilks, D. Latchman, R. Harvey, B. Dallapiccola, G. Auburger, N. Wood   +21 more
semanticscholar   +1 more source

Targeted Local Delivery via Fiber‐Embedded Flexible Microchannels Integrated with Film‐Based Implantable Probes

Advanced Materials Technologies, EarlyView.
In this study, a fiber‐embedded drug delivery channel for implantable microprobes, demonstrating the first functional drug delivery system using flexible LCP‐based probes, is developed. The design incorporates fibers for site‐selective drug delivery and electrical functions. The utilization of monolithic thermal bonding simplifies fabrication.
Jaehwan Byun, Jungseub Lee, Hyun Ryul Ryu, Geun Jae Lee, Sung Eun Lee, Sung June Kim, Noo Li Jeon   +6 more
wiley   +1 more source