Results 1 to 10 of about 65,912 (274)

APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease

Frontiers in Neurology, 2021
Introduction: Cognitive decline and dementia are common and debilitating non-motor phenotypic features of Parkinson's disease with a variable severity and time of onset.
Jon-Anders Tunold, Jon-Anders Tunold, Hanneke Geut, J. M. Annemieke Rozemuller, Sandra Pilar Henriksen, Mathias Toft, Mathias Toft, Wilma D. J. van de Berg, Lasse Pihlstrøm   +8 more
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Sex differences in clinical cognitive impairment with Lewy bodies: a Chinese multicenter study

Biology of Sex Differences, 2022
Highlights There are significant sex differences in Chinese population with cognitive impairment in Lewy body disease. Women were more common in dementia with Lewy bodies and mild cognitive impairment with Lewy bodies cases, had more frequent and severe ...
Jinghuan Gan, Zhichao Chen, Zhihong Shi, Xudong Li, Shuai Liu, Yiming Liu, Hongcan Zhu, Lu Shen, Guili Zhang, Yong You, Qihao Guo, Nan Zhang, Yang Lv, Baozhi Gang, Junliang Yuan, Yong Ji   +15 more
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Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT

Programme Grants for Applied Research, 2021
Background: Lewy body dementia, comprising both dementia with Lewy bodies and Parkinson’s disease dementia, is the second commonest cause of neurodegenerative dementia.
John T O’Brien, John-Paul Taylor, Alan Thomas, Claire Bamford, Luke Vale, Sarah Hill, Louise Allan, Tracy Finch, Richard McNally, Louise Hayes, Ajenthan Surendranathan, Joseph Kane, Alexandros E Chrysos, Allison Bentley, Sally Barker, James Mason, David Burn, Ian McKeith   +17 more
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Behavioral and psychological symptoms in neurodegenerative dementias: harbinger, follower, or constant collateral?

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Neurodegenerative dementias such as the behavioral variant of frontotemporal dementia, Alzheimer’s disease, and Parkinson’s disease dementia are linked to various behavioral and psychological abnormalities.
Souvik Dubey, Mahua Jana Dubey, Ritwik Ghosh, Debaleena Mukherjee, Alak Pandit, Julian Benito-León   +5 more
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A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

Nature Communications, 2020
The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.
Devika Agarwal, Cynthia Sandor, Viola Volpato, Tara M. Caffrey, Jimena Monzón-Sandoval, Rory Bowden, Javier Alegre-Abarrategui, Richard Wade-Martins, Caleb Webber   +8 more
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Road proximity, air pollution, noise, green space and neurologic disease incidence: a population-based cohort study

Environmental Health, 2020
Background Emerging evidence links road proximity and air pollution with cognitive impairment. Joint effects of noise and greenness have not been evaluated.
Weiran Yuchi, Hind Sbihi, Hugh Davies, Lillian Tamburic, Michael Brauer   +4 more
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Survival and years of life lost in various aetiologies of dementia, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) in Norway. [PDF]

PLoS ONE, 2018
INTRODUCTION:Alzheimer's disease patients are reported to have higher survival rate compared to patients with vascular dementia or dementia with Lewy bodies.
Bjørn Heine Strand, Anne-Brita Knapskog, Karin Persson, Trine Holt Edwin, Rachel Amland, Marit Mjørud, Espen Bjertness, Knut Engedal, Geir Selbæk   +8 more
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Dementia risk in Parkinson’s disease is associated with interhemispheric connectivity loss and determined by regional gene expression

NeuroImage: Clinical, 2020
Parkinson’s dementia is a common and devastating part of Parkinson’s disease. Whilst timing and severity vary, dementia in Parkinson’s is often preceded by visual dysfunction.
Angeliki Zarkali, Peter McColgan, Mina Ryten, Regina H. Reynolds, Louise-Ann Leyland, Andrew J. Lees, Geraint Rees, Rimona S. Weil   +7 more
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A new visual rating scale for Ioflupane imaging in Lewy body disease

NeuroImage: Clinical, 2018
Background: Dopaminergic loss on 123I-Ioflupane brain imaging is a recognised biomarker for dementia with Lewy bodies. It is usually assessed using a visual rating scale developed for Parkinson's disease, which may not be optimal for dementia with Lewy ...
Jim J. Lloyd, George Petrides, Paul C. Donaghy, Sean J. Colloby, Johannes Attems, John T. O'Brien, Gemma Roberts, Alan J. Thomas   +7 more
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Cortical Lewy Body Dementia

Behavioural Neurology, 1990
In cortical Lewy body dementia the distribution of Lewy bodies in the nervous system follows that of Parkinson's disease, except for their greater profusion in the cerebral cortex. The cortical tangles and plaques of Alzheimer pathology are often present,
W. R. G. Gibb
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