Results 11 to 20 of about 693,546 (355)

Parkinson's Syndrome Secondary to Congenital Absence of the Left Internal Carotid Artery: a Case Report and Review of the Literature [PDF]

Zhongguo quanke yixue, 2023
Congenital absence of the internal carotid artery (ICA) is a rare congenital developmental anomaly, which is often associated with carotid canal atresia and structural abnormalities of the ICA. It may be asymptomatic, or shows noticeable symptoms such as
SUN Xiaoling, LI Zhijun
doaj   +1 more source

Refractory Seizures Secondary to Vitamin B6 Deficiency in Parkinson Disease: The Role of Carbidopa-Levodopa

Case Reports in Neurology, 2022
Carbidopa-levodopa has been used for more than 50 years in the treatment of Parkinson disease (PD) and other movement disorders. Pyridoxal 5′-phosphate (PLP), an active form of vitamin B6 (pyridoxine), is involved in the decarboxylation of levodopa to ...
Adina Wise, Hernan Nicolas Lemus, Madeline Fields, Matthew Swan, Susan Bressman   +4 more
doaj   +1 more source

Retinal Optical Coherence Tomography Features Associated With Incident and Prevalent Parkinson Disease

Neurology, 2023
Background and Objectives Cadaveric studies have shown disease-related neurodegeneration and other morphological abnormalities in the retina of individuals with Parkinson disease (PD); however, it remains unclear whether this can be reliably detected ...
S. Wagner, David Romero-Bascones, M. Cortina–Borja, Dominic J. Williamson, R. Struyven, Yukun Zhou, Salil Patel, R. Weil, C. Antoniades, E. Topol, Edward Korot, P. Foster, K. Balaskas, Unai Ayala, Maitane Barrenechea, I. Gabilondo, A. Schapira, A. Khawaja, P. Patel, J. Rahi, A. Denniston, Axel Petzold, P. Keane   +22 more
semanticscholar   +1 more source

Rationale and design to evaluate the PRIME Parkinson care model: a prospective observational evaluation of proactive, integrated and patient-centred Parkinson care in The Netherlands (PRIME-NL)

BMC Neurology, 2021
Background Culminating evidence shows that current care does not optimally meet the needs of persons with parkinsonism, their carers and healthcare professionals.
Jan H. L. Ypinga, Angelika D. Van Halteren, Emily J. Henderson, Bastiaan R. Bloem, Agnes J. Smink, Emma Tenison, Marten Munneke, Yoav Ben-Shlomo, Sirwan K. L. Darweesh   +8 more
doaj   +1 more source

Targeting Mitochondria by Plant Secondary Metabolites: A Promising Strategy in Combating Parkinson’s Disease [PDF]

International Journal of Molecular Sciences, 2021
Parkinson’s disease (PD) is one of the most prevalent and debilitating neurodegenerative conditions, and is currently on the rise. Several dysregulated pathways are behind the pathogenesis of PD; however, the critical targets remain unclear. Accordingly, there is an urgent need to reveal the key dysregulated pathways in PD.
Sajad Fakhri, Sadaf Abdian, Seyede Nazanin Zarneshan, Esra Küpeli Akkol, Mohammad Hosein Farzaei, Eduardo Sobarzo-Sánchez   +5 more
openaire   +3 more sources

Extrapyramidal syndrome in psychotic depression: a case report.

European Psychiatry, 2023
Introduction Psychotic depression is a subtype of major depression, with worst prognosis but underdiagnosed and undertreated. We introduce the case of a 75-year-old patient who is attended in the hospital presenting sorrow and behavioral disturbances ...
C. Álvarez, A. M. Gómez Martín
doaj   +1 more source

Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease.

New England Journal of Medicine, 2023
BACKGROUND Unilateral focused ultrasound ablation of the internal segment of globus pallidus has reduced motor symptoms of Parkinson's disease in open-label studies.
V. Krishna, P. Fishman, H. Eisenberg, M. Kaplitt, G. Baltuch, J. Chang, Wei-Chieh Chang, R. Martínez Fernández, Marta Del Álamo, C. Halpern, P. Ghanouni, R. Eleopra, Rees G. Cosgrove, J. Guridi, R. Gwinn, Pravin Khemani, A. Lozano, N. McDannold, A. Fasano, M. Constantinescu, I. Schlesinger, Arif Dalvi, W. Elias   +22 more
semanticscholar   +1 more source

An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants

Nature Communications, 2023
A pro-inflammatory intestinal microbiome is characteristic of Parkinson’s disease (PD). Prebiotic fibers change the microbiome and this study sought to understand the utility of prebiotic fibers for use in PD patients.
Deborah Hall, R. Voigt, T. Cantu-Jungles, B. Hamaker, P. Engen, M. Shaikh, Shohreh Raeisi, S. Green, A. Naqib, C. Forsyth, Tingting Chen, Richard A. Manfready, B. Ouyang, H. Rasmussen, S. Sedghi, C. Goetz, A. Keshavarzian   +16 more
semanticscholar   +1 more source

Toward understanding ambulatory activity decline in Parkinson disease [PDF]

, 2015
BACKGROUND: Declining ambulatory activity represents an important facet of disablement in Parkinson disease (PD). OBJECTIVE: The primary study aim was to compare the 2-year trajectory of ambulatory activity decline with concurrently evolving facets of ...
Cavanaugh, James T., Dibble, Leland E., Earhart, Gammon M., Ellis, Terry D., Ford, Matthew P., Foreman, K. Bo   +5 more
core   +1 more source

Review on potential phytocompounds in drug development for Parkinson disease: A pharmacoinformatic approach

Informatics in Medicine Unlocked, 2016
Parkinson's disease (PD) is caused by human physiological function and is ranked as the second most common neurodegenerative disorder. One of the prominent therapies currently available for PD is the use of dopamine agonists which mimic the natural ...
S. Vijayakumar, S. Prabhu, S. Rajalakhsmi, P. Manogar   +3 more
doaj   +1 more source