Results 11 to 20 of about 37,807 (264)

Lactoferrin: neuroprotection against Parkinson's disease and secondary molecule for potential treatment

Frontiers in Aging Neuroscience, 2023
Parkinson's disease (PD) is the second-most common neurodegenerative disease and is largely caused by the death of dopaminergic (DA) cells. Dopamine loss occurs in the substantia nigra pars compacta and leads to dysfunctions in motor functions. Death of DA cells can occur with oxidative stress and dysfunction of glial cells caused by Parkinson-related ...
Duman, HATİCE, Karav, SERCAN, Pekdemir, Burcu, Bolat, Ecem, Eker, Furkan   +4 more
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Extrapyramidal syndrome in psychotic depression: a case report.

European Psychiatry, 2023
Introduction Psychotic depression is a subtype of major depression, with worst prognosis but underdiagnosed and undertreated. We introduce the case of a 75-year-old patient who is attended in the hospital presenting sorrow and behavioral disturbances ...
C. Álvarez, A. M. Gómez Martín
doaj   +1 more source

Review on potential phytocompounds in drug development for Parkinson disease: A pharmacoinformatic approach

Informatics in Medicine Unlocked, 2016
Parkinson's disease (PD) is caused by human physiological function and is ranked as the second most common neurodegenerative disorder. One of the prominent therapies currently available for PD is the use of dopamine agonists which mimic the natural ...
S. Vijayakumar, S. Prabhu, S. Rajalakhsmi, P. Manogar   +3 more
doaj   +1 more source

Levodopa Responsiveness in Adult‐onset Lower Limb Dystonia is Associated with the Development of Parkinson's Disease

Tremor and Other Hyperkinetic Movements, 2013
Background: Adult‐onset primary lower limb dystonia (AOPLLD) has been reported as an early sign of Parkinson’s disease (PD) or Parkinson‐plus syndrome in case series.
Florence C. F. Chang, Keith A. Josephs
doaj   +1 more source

A Pilot Study of the Feasibility and Effects of Table Tennis Training in Parkinson Disease

Archives of Rehabilitation Research and Clinical Translation, 2020
Objective: To investigate feasibility and effects of table tennis training on balance control and physical function in individuals with Parkinson disease. Design: Single group, observational, before-after trial.
Karin Olsson, MD, Erika Franzén, PT, PhD, Anders Johansson, MD, PhD   +2 more
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Clinical determinants of primary and secondary fatigue in patients with Parkinson’s disease [PDF]

Journal of Neurology, 2013
Clinical and psychosocial factors associated separately with primary and secondary fatigue in Parkinson's disease (PD) patients have not been thoroughly studied before. The aim of our study was to assess factors associated with different fatigue domains in groups with primary and secondary fatigue in PD separately.
Skorvanek, Matej, Nagyova, Iveta, Rosenberger, Jaroslav, Krokavcova, Martina, Saeedian, Radka Ghorbani, Groothoff, Johan W., Gdovinova, Zuzana, van Dijk, Jitse P.   +7 more
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Utilising telehealth to support exercise and physical activity in people with Parkinson disease: a program evaluation using mixed methods

BMC Health Services Research, 2023
Background Physical activity and exercise play a key role in managing Parkinson disease. This study aimed to: 1) determine if physiotherapy supported by telehealth helped people with Parkinson disease (PwP) to adhere to a home-based exercise program and ...
Allyson Flynn, Elisabeth Preston, Sarah Dennis, Colleen G. Canning, Natalie E. Allen   +4 more
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Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial

EBioMedicine, 2022
Summary: Background: Synucleinopathies such as Parkinson ́s disease (PD), Dementia with Lewy bodies (DLB) and Multiple System Atrophy (MSA) are characterized by deposition of misfolded and aggregated α-synuclein.
Johannes Levin, Nand Sing, Sue Melbourne, Amber Morgan, Carla Mariner, Maria Grazia Spillantini, Michal Wegrzynowicz, Jeffrey W. Dalley, Simon Langer, Sergey Ryazanov, Andrei Leonov, Christian Griesinger, Felix Schmidt, Daniel Weckbecker, Kai Prager, Torsten Matthias, Armin Giese   +16 more
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Quality of life of a person with Parkinson's disease and the relationship between the time of evolution and the severity of the disease Calidad de vida de las personas con enfermedad de Parkinson y su relación con la evolución en el tiempo y la gravedad de la enfermedad Qualidade de vida de indivíduos com Parkinson e sua relação com tempo de evolução e gravidade da doença

Revista Latino-Americana de Enfermagem, 2012
Parkinson's disease can cause disability and decrease the quality of life in its sufferers. The aim of this study was to evaluate the quality of life of a group of people with Parkinson's disease and whether a relationship exists between time of ...
Fabiana Magalhães Navarro-Peternella, Sonia Silva Marcon   +1 more
doaj   +1 more source

Constrictive pericarditis and pleuropulmonary fibrosis secondary to cabergoline treatment for Parkinson’s disease [PDF]

Heart, 2004
A 63 year old man with a six year history of Parkinson’s disease presented with signs of right heart failure following a knee replacement. Constrictive pericarditis was diagnosed and a radical pericardectomy performed. Six months later, the patient remained unwell with raised inflammatory markers. An inflammatory fibrotic reaction caused by cabergoline
M, Townsend, D H, MacIver
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