Computerized cognitive training vs. care as usual to strengthen cognitive, motor, and (neuro)psychological outcomes in people with advanced Parkinson's disease (TrainParC-Advanced): study protocol of a randomized controlled trial. [PDF]
Olgemöller PM +5 more
europepmc +1 more source
Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy +13 more
wiley +1 more source
The efficacy and safety of acupuncture for Parkinson's disease insomnia: a systematic review and meta-analysis. [PDF]
Gu Y, Liang Y, Han H, Yin H, Zheng Z.
europepmc +1 more source
Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology
The neurologist cares for patients with complex chronic conditions that compromise their wellbeing. Many such disorders are poorly understood. Whereas for some, effective symptomatic treatments exist, for most we lack an understanding of the molecular and cellular bases for disease pathogenesis needed for discovering disease‐modifying treatments ...
Fadel Zeidan +2 more
wiley +1 more source
Low to moderate relationships between gait and postural responses in Parkinson disease [PDF]
Duncan, Ryan P +4 more
core +1 more source
Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang +7 more
wiley +1 more source
Effects of a Four-Strain Probiotic on Gut Microbiota, Inflammation, and Symptoms in Parkinson's Disease: A Randomized Clinical Trial. [PDF]
Leta V +30 more
europepmc +1 more source
Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi +10 more
wiley +1 more source
Early-Onset Parkinson's Disease: Unique Features and Management Approaches. [PDF]
Hickman J +8 more
europepmc +1 more source
Objective Assess the performance of serum phosphorylated tau 217 (p‐tau217) and neurofilament light chain (NfL) in predicting risk of cognitive impairment or phenoconversion to dementia in individuals with iRBD. Methods We measured serum p‐tau217 and NfL levels by electrochemiluminescence across 4 polysomnographically confirmed iRBD cohorts (n = 300 ...
Shijun Yan +7 more
wiley +1 more source

