Results 301 to 310 of about 693,546 (355)

Clawhand deformity presumed secondary to Parkinson's disease

The Journal of Hand Surgery, 1985
A clawhand deformity presumed to be secondary to Parkinson's disease is described. No such association was found previously recorded in the literature. The marked limitation in hand function was improved by lengthening the extensor tendons, a 4-tail superficialis transfer to the intrinsic muscles, and capsulotomy of the metacarpophalangeal joints of ...
P R, Heinzelmann, R W, Dow
openaire   +2 more sources

Pathological gambling secondary to dopaminergic therapy in Parkinson's disease

Psychiatry Research, 2006
We describe six patients with Parkinson's disease (PD) and pathological gambling. All patients started gambling after the onset of PD and initiation or increase of treatment with dopaminergic therapy. The fact that pathological behaviour disappeared as medication was ended or decreased suggests that an elaborate behavioural manifestation could be ...
Dominique, Drapier, Sophie, Drapier, Paul, Sauleau, Pascal, Derkinderen, Philippe, Damier, Herve, Allain, Marc, Vérin, Bruno, Millet   +7 more
openaire   +2 more sources

The distribution of ancestral secondary cases in Parkinson's disease

Clinical Genetics, 1977
Recent evidence suggests a genetic mode of transmission of Parkinson's disease. A multifactorial mechanism is likely, but autosomal dominance with reduced penetrance has not been excluded.The distribution of ancestral second‐degree relatives with Parkinson's disease was evaluated in 12 families.
W I, Young, W E, Martin, V E, Anderson
openaire   +2 more sources

Alteration of Gut Microbial Metabolites in the Systemic Circulation of Patients with Parkinson’s Disease

Journal of Parkinson's Disease, 2022
Background: Emerging evidence suggests that gut dysbiosis contributes to Parkinson’s disease (PD) by signaling through microbial metabolites. Hippuric acid (HA), indole derivatives, and secondary bile acids are among the most common gut metabolites ...
Szu-Ju Chen, Chieh-Chang Chen, Hsin-Yu Liao, Yu-Wei Wu, Jyh-Ming Liou, Ming-Shiang Wu, C. Kuo, Chin-Hsien Lin   +7 more
semanticscholar   +1 more source

Naming in dementia secondary to Parkinson's, Huntington's, and Alzheimer's diseases

Journal of Communication Disorders, 1996
Confrontation naming problems have been found in patients with dementia secondary to Alzheimer's (AD), Huntington's (HD), and in a subset of Parkinson's disease (PD) patients with dementia. The source of the naming deficit has not been established.
E M, Frank, H L, McDade, W K, Scott
openaire   +2 more sources

Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease

Nature
Parkinson’s disease is caused by the loss of dopamine neurons, causing motor symptoms. Initial cell therapies using fetal tissues showed promise but had complications and ethical concerns1, 2, 3, 4–5.
N. Sawamoto, D. Doi, E. Nakanishi, Masanori Sawamura, Takayuki Kikuchi, H. Yamakado, Yosuke Taruno, Atsushi Shima, Yasutaka Fushimi, Tomohisa Okada, Tetsuhiro Kikuchi, A. Morizane, Satoe Hiramatsu, T. Anazawa, Takero Shindo, Kentaro Ueno, Satoshi Morita, Yoshiki Arakawa, Yuji Nakamoto, Susumu Miyamoto, R. Takahashi, Jun Takahashi   +21 more
semanticscholar   +1 more source

Key Activities of Caregivers for Individuals With Parkinson Disease: A Secondary Analysis

Journal of Neuroscience Nursing, 2020
ABSTRACT BACKGROUND: Individuals with Parkinson disease (PD) require support from family caregivers because of decreased functional levels in a later stage. Much of the research with PD caregivers has been limited by relatively homogenous samples of primarily White and largely spousal caregivers.
Ju Young, Shin, Barbara, Habermann
openaire   +2 more sources

Educational Information Improves Listener Attitudes Toward People With Dysarthria Secondary to Parkinson's Disease

American Journal of Speech-Language Pathology, 2023
Purpose: People with dysarthria have been rated as less confident and less likable and are often assumed by listeners to have reduced cognitive abilities relative to neurotypical speakers. This study explores whether educational information about dysarthria can shift these attitudes in a group of speakers with hypokinetic ...
Annalise R. Fletcher, Madison W. Potts, Stephanie A. Borrie   +2 more
openaire   +2 more sources

Trial of Lixisenatide in Early Parkinson's Disease.

New England Journal of Medicine
BACKGROUND Lixisenatide, a glucagon-like peptide-1 receptor agonist used for the treatment of diabetes, has shown neuroprotective properties in a mouse model of Parkinson's disease.
Wassilios G. Meissner, Philippe Remy, C. Giordana, D. Maltête, P. Derkinderen, J. Houeto, Mathieu Anheim, I. Benatru, Thomas Boraud, C. Brefel-Courbon, Nicolas Carrière, Hélène Catalá, Olivier Colin, J. Corvol, P. Damier, Estelle Dellapina, D. Devos, S. Drapier, Margherita Fabbri, V. Ferrier, A. Foubert-Samier, Solène Frismand-Kryloff, A. Georget, Christine Germain, Stéphane Grimaldi, Clémence Hardy, L. Hopes, Pierre Krystkowiak, B. Laurens, R. Lefaucheur, L. Mariani, A. Marquès, Claire Marsé, F. Ory-Magne, Vincent Rigalleau, Hayet Salhi, Amandine Saubion, S. Stott, C. Thalamas, Claire Thiriez, M. Tir, Richard K. Wyse, Antoine Bénard, O. Rascol   +43 more
semanticscholar   +1 more source

Alexithymia in Parkinson’s Disease: Secondary Phenomenon Or Primary Neuropsychiatric feature?

Neurodegenerative Disease Management, 2012
ISSN 1758-2024 10.2217/NMT.12.31 © 2012 Future Medicine Ltd Neurodegen. Dis. Manage. (2012) 2(4), 343–346 part of Parkinson’s disease (PD) is a neuro­ degenerative disorder previously thought to be almost exclusively characterized by motor symptoms such as rigidity, brady­ kinesia, postural instability and rest tremor.
Gianfranco Spalletta, Francesca Assogna, Carlo Caltagirone   +2 more
openaire   +1 more source