Results 51 to 60 of about 40,297 (296)

Estratégias ambientais como alternativas para a prevenção de sintomas de ansiedade e depressão em um modelo experimental da doença de Parkinson em ratos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2011A doença de Parkinson (DP) é uma doença multifatorial que se caracteriza pela degeneração ...
Savoldi, Robson
core  

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Qualificação do serviço farmacêutico clínico a partir dos dados de seguimento farmacoterapêutico a indivíduos com Doença de Parkinson [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Assistência Farmacêutica, Florianópolis, 2014.Introdução: A Doença de Parkinson (DP) é uma doença neurodegenerativa que se ...
Foppa, Aline Aparecida
core  

Akinetic rigid syndrome: An overview

Annals of Indian Academy of Neurology, 2007
Akinetic-rigid syndromes can be caused by diverse etiologies. It is vital to separate idiopathic Parkinson′s disease from other neurodegenerative diseases and causes of secondary parkinsonism as it has significant therapeutic implications. However
Gupta Praveen, Behari Madhuri
doaj  

Proteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions

Scientific Reports, 2022
Intrinsically disordered proteins (IDPs) have been in the spotlight for their unique properties, such as their lack of secondary structures and low sequence complexity.
Hongsun Park, Tomoyuki Yamanaka, Nobuyuki Nukina   +2 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease

Journal of Neuroinflammation, 2011
Background Parkinson's disease is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. The cause of the neurodegeneration is unknown.
Hudson Charles E, Bachstetter Adam D, Pabon Mibel M, Gemma Carmelina, Bickford Paula C   +4 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

O estudo das cefaleias primárias na doença de parkinson e na epilepsia do lobo temporal mesial associada à esclerose do hipocampo [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2013.Justificativa: As cefaleias primárias apresentam uma alta prevalência na população geral.
Nunes, Jean Costa
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source