Results 111 to 120 of about 9,346,254 (401)

Sailing Stormy Seas: The Illness Experience of Persons with Parkinson\u27s Disease [PDF]

, 2010
Parkinson\u27s disease is a chronic, progressive disorder with no known cause or promising cure. While substantial information is known about the pathophysiology, little is known about the illness experience of living with the disease.
Engebretson, Joan, Stanley-Hermanns, Melinda   +1 more
core   +1 more source

The therapeutic potential of exercise to improve mood, cognition, and sleep in Parkinson's disease [PDF]

, 2015
Published in final edited form as: Mov Disord. 2016 January ; 31(1): 23–38. doi:10.1002/mds.26484.In addition to the classic motor symptoms, Parkinson's disease (PD) is associated with a variety of nonmotor symptoms that significantly reduce quality of ...
Cronin‐Golomb, Alice, Ellis, Terry D., Otto, Michael W., Reynolds, Gretchen O.   +3 more
core   +1 more source

Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach

Advanced Functional Materials, EarlyView.
A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma, Om Shanker Tiwari, Vijay Kumar Patel, Ruchi Shukla, Ehud Gazit, Pandeeswar Makam   +5 more
wiley   +1 more source

Association of metabolic syndrome and change in Unified Parkinson\u27s Disease Rating Scale scores. [PDF]

, 2017
OBJECTIVE: To explore the association between metabolic syndrome and the Unified Parkinson\u27s Disease Rating Scale (UPDRS) scores and, secondarily, the Symbol Digit Modalities Test (SDMT).
Bainbridge, Jacquelyn L., Boyd, James T, Cambi, Franca, Christine, Chadwick W., Dhall, Rohit, Leehey, Maureen, Luo, Sheng, Pérez, Adriana, Schneider, Jay S, Sharma, Saloni, Simon, David K., Singer, Carlos, Wills, Anne-Marie A., Wong, Pei Shieen, Zhang, Yunxi   +14 more
core   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Protein Aggregates and Polyglutamine Tracts In Neurodegenerative Disease [PDF]

, 2018
The incidence of neurodegenerative diseases such as Alzheimer\u27s Disease, Parkinson\u27s Disease, Huntington\u27s Disease and other Polyglutamine Diseases is projected to dramatically increase throughout the developed world, and yet the pathology of ...
Mack, John
core   +1 more source

Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation [PDF]

, 2009
Background: Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1).
A Colao, A Colao, AJ van der Lely, AL Barkan, AN Paisley, AN Paisley, AS Bates, C Parkinson, C Parkinson, C Parkinson, C Parkinson, C Parkinson, Cambridgeshire joint prescribing group decision document, D Moore, David J Moore, G Didoni, G Sesmilo, H Biering, I Schreiber, IM Holdaway, J Ayuk, J Feenstra, JO Jorgensen, Martin J Connock, NHS Centre for Reviews and Dissemination University of York, NR Biermasz, P Chanson, Pfizer Limited, PJ Trainer, R Kauppinen-Makelin, R Kauppinen-Makelin, R Pivonello, R Trepp, S Jehle, S Melmed, SC Hua, SM Orme, SM Webb, Sue Bayliss, SV Rowles, VS Bonert, Welsh Medicines Partnership, WP Fairfield, Yaser Adi   +43 more
core   +4 more sources

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson\u27s Disease. [PDF]

, 2015
UNLABELLED: The striatum is essential for many aspects of mammalian behavior, including motivation and movement, and is dysfunctional in motor disorders such as Parkinson\u27s disease.
Case, Daniel T., Collier, Timothy J., Divito, Christopher B., Edwards, Robert H., Rubio, Maria E., Seal, Rebecca P., Sortwell, Caryl E., Stancati, Jennifer A., Steece-Collier, Kathy, Sulzer, David, Williams, Sean-Paul G., Zhang, Hui, Zhi, Lianteng   +12 more
core   +1 more source