Results 151 to 160 of about 98,362 (265)

Bioprinted Organoids: An Innovative Engine in Biomedicine

Advanced Science, EarlyView.
Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li, Kai Li, Cheng Zhang, Yingying Zhao, Yiyuan Guo, Jia He, Shiyuan Chang, Xinyi Fang, Kaizheng Liu, Pingping Zhu, Zhenzhen Chen, Changshun Ruan   +11 more
wiley   +1 more source

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

Advanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang, Qing Wang, Minghao Zhou, Jialu Liang, Lei You, Breton Asken, Xiaobo Zhou, Qianqian Song   +7 more
wiley   +1 more source

Proximity to Golf Courses and Risk of Parkinson Disease.

JAMA Netw Open
Krzyzanowski B, Mullan AF, Dorsey ER, Chirag SS, Turcano P, Camerucci E, Bower JH, Savica R.   +7 more
europepmc   +1 more source

Gait Initiation in Community-Dwelling Adults With Parkinson Disease: Comparison With Older and Younger Adults Without the Disease

, 2002
Matthew Martin, Mindi Shinberg, Maggie Kuchibhatla, Laurie Ray, James Carollo, Margaret Schenkman   +5 more
openalex   +1 more source

A Controlled, Randomized, Delayed-Start Study of Rasagiline in Early Parkinson Disease [PDF]

, 2004

openalex   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Characteristics of responders to interventions for Parkinson disease: a scoping systematic review. [PDF]

Neurodegener Dis Manag
Baudendistel ST, Earhart GM.
europepmc   +1 more source

Dopamine Transporter Brain Imaging to Assess the Effects of Pramipexole vs Levodopa on Parkinson Disease Progression

, 2002
Parkinson Study Group
openalex   +1 more source

Elevated Plasma Homocysteine Level in Patients With Parkinson Disease [PDF]

, 2004
Padraig O’Suilleabhain, Victor Sung, Carlos Hernández, Laura H. Lacritz, Richard B. Dewey, Teodoro Bottiglieri, Ramon Diaz‐Arrastia   +6 more
openalex   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source