Results 151 to 160 of about 90,745 (249)

Molecularly Engineered Phenoxazinone‐Skeleton Cascade‐Activated NIR Probes for Monitoring Fe2+/Viscosity in Ferroptosis‐Mediated Parkinson's Disease

Advanced Science, EarlyView.
A series of Fe2+/viscosity cascade‐activated NIR fluorescence probes (NP1–5) are synthesized, and NP3 is selected for its optimal properties. To verify application of NP3 in ferroptosis intervention in PD, PQR NPs, is constructed by NP3 and quercetin self‐assembling.
Lixia Guo, Tao Liu, Hongfei Wang, Qi Gao, Zhaobo Yang, Zumeng Wang, Chenlong Li, Yubing Kang, Kahleong Lim, Wen Liu, Li Lu, Chengwu Zhang   +11 more
wiley   +1 more source

Effects of Telehealth Interventions for People With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

JMIR Mhealth Uhealth
Sun M, Tang F, Min L, Wen S, Wang S, Jiang H.   +5 more
europepmc   +1 more source

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang, Chunyan Xiang, Liangxiao Zhang, Peiwu Li   +3 more
wiley   +1 more source

A bibliometric analysis of non-coding RNAs in Parkinson disease: Research hotspots and emerging trends (2013-2022). [PDF]

Medicine (Baltimore)
Zhu L, Chen D, Wang X, He C.
europepmc   +1 more source

The Evolution of Symptoms in Prodromal Dementia With Lewy Bodies: A Naturalistic History Study in a Chinese Memory Clinic

AGING MEDICINE, EarlyView.
The study characterized the evolution of symptoms prior to a diagnosis of DLB in people attending a Chinese memory clinic. Anxiety was the earliest recognized individual psychiatric symptom of DLB, followed by depression and memory decline. ABSTRACT Objectives Given that DLB is the second most common neurodegenerative dementia and early detection is ...
Ming Zhang, Tao Li, Dag Aarsland, Xiaozhen Lv, Jing Wang, Teng Xie, Xin Yu, Huali Wang   +7 more
wiley   +1 more source

White Matter Structural Network Dysfunction Mediates the Effect of Hypertension on Cognitive Decline in Parkinson Disease. [PDF]

Neurologist
Shu L, Li S, Lin L, Yu Y, Liao B, Lu T.
europepmc   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Quantifying Slowness in Parkinson Disease Using a Serious Game: Cross-Sectional Study.

JMIR Serious Games
Mendes LC, Cabral AM, Alves CM, Marques IA, Delis AL, Morère Y, Andrade AO.   +6 more
europepmc   +1 more source

Revisiting the 2015 MDS diagnostic criteria for Parkinson disease: insights from autopsy-confirmed cases. [PDF]

NPJ Parkinsons Dis
Fox SH, Luca DG, Postuma RB, Bhidayasiri R, Cardoso F, Kovacs GG, Katzenschlager R, Trenkwalder C.   +7 more
europepmc   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source