Results 141 to 150 of about 93,640 (252)

Striatal Dopamine Transporter and Rest Tremor in Parkinson Disease: A Clinical Validation. [PDF]

Neurology
Niemi KJ, Jaakkola E, Myller EM, Eklund MRE, Nuuttila S, Mertsalmi T, Murtomäki KM, Levo R, Noponen T, Ihalainen T, Scheperjans F, Joutsa J, Kaasinen V.   +12 more
europepmc   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Feasibility for a Community-Based Parkinson Disease Cohort in Hawaii. [PDF]

Neurol Clin Pract
Krening E, Shuman R, Faouzi M, Thai K, Gao F, Tanner CM, Ross GW, Bruno MK.   +7 more
europepmc   +1 more source

Parkinson's disease. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1990
openaire   +5 more sources

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

Parkinson Disease Pathogenic Variants: Cross-Ancestry Analysis and Microarray Data Validation. [PDF]

Neurol Genet
Hong S, Koretsky MJ, Lichtenberg J, Leonard HL, Pitz V, as the Global Parkinson's Genetics Program (GP2).   +5 more
europepmc   +1 more source

Parkinson's Disease

Neurobiology of Disease, 2000
openaire   +3 more sources

G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation

Advanced Science, EarlyView.
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang, Qingqing Xu, Yuxin Zhang, Fang Liu, Guangchao Sui, Dangdang Li   +5 more
wiley   +1 more source

Genetic Testing by Age at Onset in Parkinson Disease.

JAMA Neurol
Balck A, Vollstedt EJ, Westenberger A, Lange LM, Trinh J, Kasten M, Lohmann K, Brüggemann N, Trenkwalder C, Mollenhauer B, Alcalay R, Galvelis KG, Beck JC, Bauer P, Klein C, König IR, Global Parkinson’s Genetics Program (GP2), the ROPAD Study Group, and the PDGENEration Study.   +18 more
europepmc   +1 more source

Highly Repeatable Fibrous Crack‐Based Strain Sensor for Multichannel Continuous Tremor Monitoring in Parkinson's Disease and Essential Tremor

Advanced Science, EarlyView.
This study proposes a patch‐type tremor monitoring system based on high‐repeatable fibrous crack‐based strain sensor, capable of simultaneously measuring tremor in multiple locations such as thumb, index, and wrist. Through clinical trials involving Parkinson's disease and essential tremor patients, the proposed system demonstrates its potential as a ...
Chiwon Song, Chan Park, Juyoun Lee, Hojoong Kim, Jeongbeom Kang, Byeongjun Lee, Cheoljeong Park, Jungmin Kim, Haran Lee, Yoon Jae Lee, Min‐Kyung Yeo, Woon‐Hong Yeo, Seong J. Cho   +12 more
wiley   +1 more source