Results 271 to 280 of about 274,716 (345)

3,4-Dihydroxyphenylglycol levels separate multiple system atrophy from Parkinson disease with orthostatic hypotension. [PDF]

Clin Auton Res
Goldstein DS, Sullivan P, Holmes C.
europepmc   +1 more source

Epidemiological study on the prevalence of Parkinson’s disease, parkinsonism, and rem sleep behavior disorder in the community of Candangolândia - DF

Simoneide Souza Titze de Almeida, Isabel Oliveira Araujo Moraes, Milena Vieira Ramos, Talita Guimarães Balieiro, Gustavo Henrique Campos de Sousa, J Guimarães, Pedro Renato de Paula Brandão   +6 more
openalex   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Data-Driven Subtypes of Parkinson Disease Based on Dopamine Responsiveness. [PDF]

CNS Neurosci Ther
Wang JY, Zeng GL, Tang RT, Luo HT, Song YL, Zhou YY, Huang JF, Zhu SG, Zhang DL, Liu DN, Liu RP, Huang SS, Yuan CX, Zhu JH, Zhang X.   +14 more
europepmc   +1 more source

The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid

Advanced Science, EarlyView.
Functional bacterial amyloids such as CsgA and FapC have been widely studied to understand the relationship between aggregation and function. The recently solved structure of FapC reveals a Greek‐key motif in which extensive hydrogen bonding and packing interactions formed by residues in conserved imperfect repeats stabilize a β‐solenoid core.
Samuel Peña‐Díaz, Yanting Jiang, Zhefei Zhang, Anders Daugberg, Pedro Ferreira, Marcos López Hernández, Chandrika Mittal, Maria Joao Ramos, Jan Skov Pedersen, Morten Kam Dahl Dueholm, Cao Qin, Huabing Wang, Daniel E. Otzen   +12 more
wiley   +1 more source

Correction: Distinct spatial transcriptomic patterns of substantia Nigra in Parkinson disease and Parkinsonian subtype of multiple system atrophy. [PDF]

Acta Neuropathol Commun
Shin JH, Ruhno KE, Shin C, Kim HJ, Nam SJ, Chung SJ, Moon JH, Kim HJ.   +7 more
europepmc   +1 more source

Intelligent Sensing: The Emerging Integration of Machine Learning and Soft Sensors Based on Hydrogels and Ionogels

Advanced Science, EarlyView.
By integrating with machine learning (ML), hydrogel‐ and ionogel‐based soft sensors are gaining human brain‐like capabilities to perceive, learn, and predict. This review summarizes their advances, focusing on ML‐powered applications such as handwriting/gesture/object/motion/speech recognition, health monitoring, food detection, and beyond.
Wenqing He, Rumin Lin, Suixiu Kong, Mengyi Qiang, Lingqi Huang, Bing Dai, Xi Yao, Lei Su, Xueji Zhang   +8 more
wiley   +1 more source

Community Disadvantage Is Associated With More Severe Motor Symptoms in Parkinson Disease. [PDF]

Neurol Clin Pract
Hill EJ, Marcucci SB, DeLano K, Abanto J, Sawyer RP, Marsili L, Duque KR, Sun Q, Woo D, Langefeld CD, Hall DA, Skirpan D, Paredes NC, Spikes C, Bajaj DA, Gregor N, Stivers S, Mahajan A, Woo JG, Espay AJ.   +19 more
europepmc   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source