Results 271 to 280 of about 271,759 (355)

MRI Epicenters Differentiate Spatiotemporal Patterns of Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
A connectivity‐based MRI epicenter model identifies two Parkinson's disease subtypes: subtype 1 with infratentorial‐dominant epicenters, severe motor symptoms, and rapid progression; and subtype 2 with supratentorial‐dominant epicenters with mild progression.
Xiaojie Duanmu   +23 more
wiley   +1 more source

Proximity to Golf Courses and Risk of Parkinson Disease.

open access: yesJAMA Netw Open
Krzyzanowski B   +7 more
europepmc   +1 more source

Dissecting the Molecular Determinants of α‐synuclein Phase Separation and Condensate Aging: The Pivotal Role of β‐Sheet‐Rich Motifs

open access: yesAdvanced Science, EarlyView.
Through multiscale simulations and experimental approaches, the molecular determinants of α‐synuclein phase separation and condensate aging, which are linked to Parkinson's disease, are uncovered. Seven motifs are identified with high β‐sheet propensity in monomeric α‐synuclein and increasing β‐sheet tendencies during condensation and pre ...
Yiming Tang   +11 more
wiley   +1 more source

PNP29: CLINITRAC:A NOVEL METHOD FOR EVALUATING OUTCOME IN PARKINSON DISEASE

open access: bronze, 2003
Kerstin Bingefors   +2 more
openalex   +1 more source

Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay   +3 more
wiley   +1 more source

Impact of pimavanserin on prescribing practices in parkinson disease. [PDF]

open access: yesClin Park Relat Disord
Pham Nguyen TP   +3 more
europepmc   +1 more source

A Single‐Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration

open access: yesAdvanced Science, EarlyView.
Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao   +11 more
wiley   +1 more source

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