Results 1 to 10 of about 2,700 (139)

Long-Term Adherence and Drug Utilisation Patterns Among New Users of Anti-Hyperlipidemic Monotherapy: Development of a Risk Prediction Model. [PDF]

J Eval Clin Pract
ABSTRACT Rationale Real‐world long‐term adherence and drug patterns are essential in hyperlipidemia management. However, the evidence was unclear. Aims and Objectives This study aimed to assess long‐term adherence, drug usage patterns of anti‐hyperlipidemic monotherapy, associated risk factors, and develop risk prediction models. Methods We performed a
Li X, Hak E, Bos JHJ, Schuiling-Veninga CCM, Mubarik S.   +4 more
europepmc   +2 more sources

Factors associated with potentially inappropriate medication use, medication underuse and overuse in older adults in the German National Cohort. [PDF]

J Intern Med
Abstract Background Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug‐related harms. Methods We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO).
Degen M, Haug U, Scholle OHF, Awuku-Larbi Y, Carlsson S, Ebert N, Harth V, Hauri AM, Heier M, Herrmann A, Leitzmann M, Linseisen J, Meinke-Franze C, Obi N, Pendt P, Reinhold T, Thorand B, Brenner H, Schöttker B.   +18 more
europepmc   +2 more sources

Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese [PDF]

Arquivos de Neuro-Psiquiatria, 2020
Background: The treatment of Parkinson disease with dopaminergic therapy improves functionality and quality of life. However, as the disease progresses, the wearing-off phenomenon develops.
Carlos Eduardo MANTESE, Marcio MEDEIROS, Artur SCHUMACHER-SCHUH, Carlos Roberto de Melo RIEDER   +3 more
doaj   +1 more source

Guidelines for Parkinson’s disease treatment: consensus from the Movement Disorders Scientific Department of the Brazilian Academy of Neurology - motor symptoms

Arquivos de Neuro-Psiquiatria, 2022
The treatment of Parkinson's disease (PD) is challenging, especially since it is considered highly individualized. The Brazilian Academy of Neurology has recognized the need to disseminate knowledge about the management of PD treatment, adapting the best
Roberta Arb Saba, Débora Palma Maia, Francisco Eduardo Costa Cardoso, Vanderci Borges, Luiz Augusto F. Andrade, Henrique Ballalai Ferraz, Egberto Reis Barbosa, Carlos Roberto de Mello Rieder, Delson José da Silva, Hsin Fen Chien, Tamine Capato, Ana Lúcia Rosso, Carlos Frederico Souza Lima, José Marcelo Ferreia Bezerra, Denise Nicaretta, Orlando Graziani Povoas Barsottini, Clécio Godeiro-Júnior, Lorena Broseghini Barcelos, Rubens Gisbert Cury, Mariana Spitz, Sônia Maria César Azevedo Silva, Marcus Vinicius Della Colletta   +21 more
doaj   +1 more source

Prescribing patterns of antiparkinson drugs in a group of Colombian patients, 2015

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction: Parkinson’s disease, whose prevalence in Colombia is 4.7 per 1,000 inhabitants, is a public health problem and a therapeutic challenge for health professionals. Objective: To determine the prescribing patterns of antiparkinson drugs and the
Jorge Enrique Machado-Alba, Luis Felipe Calvo-Torres, Andrés Gaviria-Mendoza, Juan Daniel Castrillón-Spitia   +3 more
doaj   +1 more source

Antidepressant prescribing patterns and adverse events following introduction of a National Prescribing Indicator to monitor dosulepin usage in Wales

British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3596-3605, December 2023., 2023
Aims Limiting use of the antidepressant dosulepin has been encouraged due to associated risks of toxicity. In April 2011, the All Wales Medicines Strategy Group introduced a National Prescribing Indicator (NPI) to monitor dosulepin usage. The aim of this study was to investigate antidepressant prescribing patterns, and selected adverse events in ...
Katherine Chaplin, Robert C. Bracchi, Kathryn E. Haines, Philip Alexander Routledge, Paul N. Deslandes   +4 more
wiley   +1 more source

Fall-related injuries in a nursing home setting: is polypharmacy a risk factor?

BMC Health Services Research, 2009
Background Polypharmacy is regarded as an important risk factor for fallingand several studies and meta-analyses have shown an increased fall risk in users of diuretics, type 1a antiarrhythmics, digoxin and psychotropic agents.
Colli Cristiano, Costantini Chiara, Cazzamalli Sara, Poloni Nicola, Ceccon Francesca, Diurni Marcello, Baranzini Federico, Greco Laura, Callegari Camilla   +8 more
doaj   +1 more source

Medication clusters at hospital discharge and risk of adverse drug events at 30 days postdischarge: A population‐based cohort study of older adults

British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3715-3752, December 2023., 2023
Aims Certain combinations of medications can be harmful and may lead to serious adverse drug events (ADEs). Identifying potentially problematic medication clusters could help guide prescribing and/or deprescribing decisions in hospital. The aim of this study is to characterize medication prescribing patterns at hospital discharge and determine which ...
Daniala L. Weir, Xiaomeng Ma, Lisa McCarthy, Terence Tang, Lauren Lapointe‐Shaw, Walter P. Wodchis, Olavo Fernandes, Emily G. McDonald   +7 more
wiley   +1 more source

Fistulization of J-PEG Jejunal Tube into the Colon in a Patient Treated with Duodopa® Infusion: A Case Report

GE: Portuguese Journal of Gastroenterology, 2017
The continuous delivery of a levodopa/carbidopa gel suspension (Duodopa®) into the small bowel through a jejunal tube inserted via percutaneous endoscopic gastrostomy represents a new treatment method in advanced Parkinson disease.
Pedro Russo, Mariana Costa, Mário Silva, Ary de Sousa, Diana Carvalho, Joana Saiote, Milena Mendes   +6 more
doaj   +1 more source

Do Th17 Lymphocytes and IL-17 Contribute to Parkinson's Disease? A Systematic Review of Available Evidence

Frontiers in Neurology, 2019
Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive loss of dopaminergic neurons, appearance of Lewy bodies and presence of neuroinflammation.
Elisa Storelli, Niccolò Cassina, Emanuela Rasini, Franca Marino, Marco Cosentino   +4 more
doaj   +1 more source