Results 21 to 30 of about 3,715,425 (177)

[Neuromuscular disorders due to adverse effects of antiparkinson agents].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007
N. Hattori
openaire   +3 more sources

Antidepressant prescribing patterns and adverse events following introduction of a National Prescribing Indicator to monitor dosulepin usage in Wales

British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3596-3605, December 2023., 2023
Aims Limiting use of the antidepressant dosulepin has been encouraged due to associated risks of toxicity. In April 2011, the All Wales Medicines Strategy Group introduced a National Prescribing Indicator (NPI) to monitor dosulepin usage. The aim of this study was to investigate antidepressant prescribing patterns, and selected adverse events in ...
Katherine Chaplin, Robert C. Bracchi, Kathryn E. Haines, Philip Alexander Routledge, Paul N. Deslandes   +4 more
wiley   +1 more source

Medication clusters at hospital discharge and risk of adverse drug events at 30 days postdischarge: A population‐based cohort study of older adults

British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3715-3752, December 2023., 2023
Aims Certain combinations of medications can be harmful and may lead to serious adverse drug events (ADEs). Identifying potentially problematic medication clusters could help guide prescribing and/or deprescribing decisions in hospital. The aim of this study is to characterize medication prescribing patterns at hospital discharge and determine which ...
Daniala L. Weir, Xiaomeng Ma, Lisa McCarthy, Terence Tang, Lauren Lapointe‐Shaw, Walter P. Wodchis, Olavo Fernandes, Emily G. McDonald   +7 more
wiley   +1 more source

Fistulization of J-PEG Jejunal Tube into the Colon in a Patient Treated with Duodopa® Infusion: A Case Report

GE: Portuguese Journal of Gastroenterology, 2017
The continuous delivery of a levodopa/carbidopa gel suspension (Duodopa®) into the small bowel through a jejunal tube inserted via percutaneous endoscopic gastrostomy represents a new treatment method in advanced Parkinson disease.
Pedro Russo, Mariana Costa, Mário Silva, Ary de Sousa, Diana Carvalho, Joana Saiote, Milena Mendes   +6 more
doaj   +1 more source

Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents [PDF]

, 2006
The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes. Synthetic phenothiazines (with aliphatic, methylpiperazine, piperazine-ethanol,
Antonieta Valenzuela, M., Ranade, Vasant V., Mosnaim, Aron D., Puente, Javier, Wolf, Marion E.   +4 more
core   +1 more source

Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC–MS/MS method development [PDF]

, 2018
Soluble epoxide hydrolase (sEH) inhibition is reported to elevate endogenous epoxyeicosatrienoic acids (EET's), which are known to play an important role in neuroprotection by inhibiting oxidative stress and neuroinflammation. In the present study, PTUPB,
Karthik Yamjala, Lakkappa, Navya, Babu, B, Hammock, Bruce D, Praveen T. Krishnamurthy, Bruce D. Hammock, Krishnamurthy, Praveen T, Hwang, Sung Hee, Sung Hee Hwang, Navya Lakkappa, B. Babu, Yamjala, Karthik   +11 more
core   +1 more source

Changing trends in drug overdose mortality in Spain, 2001–2022

Addiction, Volume 121, Issue 2, Page 261-272, February 2026.
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné, Marta Donat, Juan Miguel Guerras, Gregorio Barrio, María José Belza, Julieta Politi, Enrique Regidor   +6 more
wiley   +1 more source

Impact of second-generation antipsychotics on the use of antiparkinson agents in nursing homes and assisted-living facilities

, 2011
BACKGROUND: It is not known whether the reduced risk of motor adverse effects with second-generation antipsychotics (SGAPs) translates into less use of antiparkinson drugs (APDs).
Brandt, Nicole J., Toure, Juliette Taylor, Briesacher, Becky A., Limcangco, M. Rhonda   +3 more
core   +1 more source

Phenanthrene Alkaloids From Guatteria Olivacea as Topoisomerase II Inhibitors: Theoretical Insights and Cytotoxic Evaluation

ChemistrySelect, Volume 11, Issue 2, 15 January 2026.
Three phenanthrene alkaloids from Guatteria olivacea were studied by DFT, docking, MD, and cytotoxicity assays. All compounds showed stable binding to DNA–topoisomerase II and human serum albumin. Atherosperminine exhibited cytotoxic activity against four cancer cell lines, supporting its potential as a topoisomerase II inhibitor and anticancer ...
Renyer A. Costa, Victor L. Tananta, Ianni de O. Corrêa, Jamelah S. Al‐Otaibi, Y. Sheena Mary, Milena Botelho P. Soares, Daniel P. Bezzera, Morgana de S. Araújo, Emmanoel V. Costa   +8 more
wiley   +1 more source

Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

BioMed Research International, Volume 2026, Issue 1, 2026.
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh, Vikas Sharma, Blessing Nnenna Udeh, Baisakhi Banerjee   +3 more
wiley   +1 more source