Results 21 to 30 of about 1,498,446 (168)

Trends in inpatient antiparkinson drug use in the USA, 2001–2012 [PDF]

, 2015
Purpose: Although therapeutic options and clinical guidelines for Parkinson's disease (PD) have changed significantly in the past 15 years, prescribing trends in the USA remain unknown.
Dylan P. Thibault, Bjerre, Lise M., Donald Mattison, Thibault, Dylan P., Kohen, Dafna E., Daniel Krewski, James A. G. Crispo, Dafna E. Kohen, Emons, Matthew, Mattison, Donald, Crispo, James, Krewski, Daniel, Lise M. Bjerre, Matthew Emons, Pérez Lloret, Santiago, Santiago Perez-Lloret, Allison W. Willis, Willis, Allison W., Yannick Fortin, Fortin, Yannick   +19 more
core   +1 more source

Formal Verification of Neural Agents in Non-deterministic Environments [PDF]

, 2020
We introduce a model for agent-environment systems where the agents are implemented via feed-forward ReLU neural networks and the environment is non-deterministic. We study the verification problem of such systems against CTL properties.
Akintunde, Michael E., Lomuscio, Alessio, Kouvaros, Panagiotis, Botoeva, Elena, Akintunde, Michael E   +4 more
core   +1 more source

Phenanthrene Alkaloids From Guatteria Olivacea as Topoisomerase II Inhibitors: Theoretical Insights and Cytotoxic Evaluation

ChemistrySelect, Volume 11, Issue 2, 15 January 2026.
Three phenanthrene alkaloids from Guatteria olivacea were studied by DFT, docking, MD, and cytotoxicity assays. All compounds showed stable binding to DNA–topoisomerase II and human serum albumin. Atherosperminine exhibited cytotoxic activity against four cancer cell lines, supporting its potential as a topoisomerase II inhibitor and anticancer ...
Renyer A. Costa, Victor L. Tananta, Ianni de O. Corrêa, Jamelah S. Al‐Otaibi, Y. Sheena Mary, Milena Botelho P. Soares, Daniel P. Bezzera, Morgana de S. Araújo, Emmanoel V. Costa   +8 more
wiley   +1 more source

Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

BioMed Research International, Volume 2026, Issue 1, 2026.
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh, Vikas Sharma, Blessing Nnenna Udeh, Baisakhi Banerjee   +3 more
wiley   +1 more source

Beyond autonomy : the self and life of social agents

, 2019
Agents have gained popularity nowadays as virtual assistants and companions of their human users supporting daily activities in many aspects of personal life.
Tan, Ah-Hwee, Subagdja, Budhitama
core   +1 more source

Social Determinants of Health and Their Association With Parkinson′s Disease Prevalence in US Adults: Insights From NHANES 2001–2020

Behavioural Neurology, Volume 2026, Issue 1, 2026.
Background Social determinants of health (SDoH) have not been comprehensively studied in relation to Parkinson′s disease (PD), although they are well known to be associated with other chronic diseases. Here we assessed the relationship of a multidimensional, comprehensive measure of SDoH with the prevalence of PD in US adults.
Jinping Fang, Detao Meng, Boyan Fang, Karsten Witt   +3 more
wiley   +1 more source

Bibliometric Analysis of Research Trends and Key Areas Related to the Relationship Between Parkinson’s Disease and Exercise Therapy

Parkinson's Disease, Volume 2026, Issue 1, 2026.
Background Exercise therapy is recognized as a crucial method that can markedly improve outcomes for individuals with Parkinson’s Disease. Research on exercise therapy and Parkinson’s Disease is steadily increasing; however, a bibliometric analysis in this field is currently lacking.
Zengkun Fang, Shuang Zeng, Dingwen Xu, Huachun Liu, Giovanni Mirabella   +4 more
wiley   +1 more source

The dynamic selection of coordination mechanisms

, 2004
This paper presents and evaluates a decision making framework that enables autonomous agents to dynamically select the mechanism they employ in order to coordinate their inter-related activities. Adopting this framework means coordination mechanisms move
Jennings, N. R., Excelente-Toledo, CB, Excelente-Toledo, C.B., Jennings, NR   +3 more
core   +1 more source

Drug Repurposing Investigation for Combating Ebola Virus Disease: Database Mining, Docking Calculations, Molecular Dynamics, and Density Functional Theory Study

ChemistryOpen, Volume 14, Issue 12, December 2025.
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman, Gamal A. H. Mekhemer, Peter A. Sidhom, Mohamed A. El‐Tayeb, Shahzeb Khan, Mahmoud A. A. Ibrahim   +5 more
wiley   +1 more source

Anti-nicotinic Properties of Anticholinergic Antiparkinson Drugs

, 1998
The nature of the antagonism by anticholinergic compounds of nicotine-induced convulsion in mice has not been defined clearly. Although, because they do not compete effectively for agonist binding to brain tissue in-vitro, these compounds are thought to ...
Z G Gao, L J Li, Q H Fan, C G Liu, W Y Cui, B Y Liu   +5 more
core   +1 more source