Results 41 to 50 of about 3,715,425 (177)

Patients' perspective on their drug therapy after bariatric surgery: A quantitative, cross‐sectional interview study

open access: yesClinical Obesity, Volume 14, Issue 5, October 2024.
Graphical abstract on the background, methods, summarized results and conclusion of the study. Summary Drug therapy in patients who have undergone bariatric surgery is challenging. We aimed to investigate the patients' perspective on their drug therapy.
Susanne Schiek   +9 more
wiley   +1 more source

Clinical trials on combination of repurposed drugs and anticancer therapies

open access: yes, 2020
This chapter provides the clinical applications of existing several therapeutic agents for the treatment of cancer which is called drug repurposing. The main aim of drug repurposing generally is that trying to find a new use of drugs or molecules that ...
Süreyya Ölgen, Ölgen, Süreyya
core   +1 more source

Prevalence of Late‐Stage Parkinson's Disease in the US Healthcare System: Insights from TriNetX

open access: yesMovement Disorders, Volume 39, Issue 9, Page 1592-1601, September 2024.
Abstract Background Patients in late‐stage Parkinson's disease (PDLS) are caregiver‐dependent, have low quality of life, and higher healthcare costs. Objective To estimate the prevalence of PDLS patients in the current US healthcare system. Methods We downloaded the 2010–2022 data from the TriNetX Diamond claims network that consists of 92 US ...
Sol De Jesus   +9 more
wiley   +1 more source

Design of agents for stimulation of neostriatal dopaminergic mechanisms

open access: yes, 1974
The structure-activity requirements for stimulation of striatal dopaminergic mechanisms were investigated using a series of phenethylamine derivatives, apomorphine and isoapomorphine, and the intracerebral injection technique for direct application into ...
R J Naylor, B Costall, R M Pinder
core   +1 more source

Serie: Medicamenten en mondzorg 5. Bijwerkingen van medicamenten en zelfzorg­middelen op gebitselementen [PDF]

open access: yes, 2017
Intrinsic tooth discoloration may occur as an adverse effect of fluoride and tetracyclines. Extrinsic tooth discoloration may occur as superficial staining or as discoloration of the superficial pellicle and/or biofilm due to chlorhexidine, liquid iron ...
Vissink, A.   +8 more
core   +1 more source

Heterogeneous treatment effects of sodium‐glucose cotransporter 2 inhibitors on risk of dementia in people with type 2 diabetes: A population‐based cohort study

open access: yesAlzheimer's &Dementia, Volume 20, Issue 8, Page 5528-5539, August 2024.
Abstract INTRODUCTION Sodium‐glucose cotransporter 2 (SGLT2) inhibitors exhibit potential benefits in reducing dementia risk, yet the optimal beneficiary subgroups remain uncertain. METHODS Individuals with type 2 diabetes (T2D) initiating either SGLT2 inhibitor or sulfonylurea were identified from OneFlorida+ Clinical Research Network (2016–2022).
Huilin Tang   +12 more
wiley   +1 more source

Optimal dose for the efficacy of asenapine in patients with schizophrenia: Real‐world data

open access: yesNeuropsychopharmacology Reports, Volume 44, Issue 1, Page 234-239, March 2024.
A meta‐analysis of large short‐term studies found no significant difference between asenapine doses of 10 and 20 mg/day for acute schizophrenia treatment. However, these studies' homogeneous patient populations may not accurately represent the diversity seen in clinical practice.
Yoshiteru Takekita   +11 more
wiley   +1 more source

Prescribing cascades in ambulatory care: A structured synthesis of evidence

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 44, Issue 1, Page 87-96, January 2024.
Abstract The strength of evidence for specific ambulatory care prescribing cascades, in which a marker drug is used to treat an adverse event caused by an index drug, has not been well characterized. To perform a structured, systematic, and transparent review of the evidence supporting ambulatory care prescribing cascades.
Faiza Shahid   +5 more
wiley   +1 more source

A Synthetic Approach to Parkinson’s Disease Drugs: Pramipexole and Rotigotine

open access: yes, 2023
In recent years, there has been numerous notable changes in Parkinson\u27s disease medication. Researchers have produced new medications and gained a firm understanding of how to employ existing treatments.
Salih, Nadia   +2 more
core  

Studies approaching at the total diasteroselective synthesis of (+)-lysergol and (+)-lysergic acid, from α,β-unsaturated diazoketones

open access: yes, 2022
Os alcaloides ergolínicos são produtos naturais produzidos pelo fungo Claviceps Purpurea, estruturalmente possuem um esqueleto tetracíclico [6,5,6,6], sendo a ergolina a estrutura base.
Vilca, Edson Emilio Garambel
core   +1 more source

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