A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research. [PDF]
The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.
Aapro +349 more
core +3 more sources
In vitro efficacy of clinically available drugs against growth and viability of Acanthamoeba castellanii keratitis isolate belonging to the T4 genotype [PDF]
The effects of clinically available drugs targeting muscarinic cholinergic, adrenergic, dopaminergic, and serotonergic receptors; intracellular calcium levels and/or the function of calcium-dependent biochemical pathways; ion channels; and cellular pumps
Baig, Abdul Mannan +2 more
core +1 more source
Oxidative Stress and Parkinson's Disease: New Hopes in Treatment with Herbal Antioxidants [PDF]
Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology.
Bahmani, Mahmoud. +3 more
core +1 more source
The Effect of Drugs in the Oral Cavity- A Review [PDF]
It is estimated that more than 2-4 % of hospital admissions are related to drug induced reactions. There is an ever expanding list of medications linked to pathologic reactions in the oral and perioral region.
Trophimus Gnanabagyan Jayakaran
core
Pharmacological interactions of vasoconstrictors [PDF]
This article is the first of a series on pharmacological interactions involving medicaments commonly prescribed and/or used in odontology: vasoconstrictors in local anaesthetics and anti-inflammatory and anti-microbial analgesics. The necessity for the
Calvo Guirado, José Luis +3 more
core
Innovation and Foreign Investment Behavior of the U.S. Pharmaceutical Industry [PDF]
This paper deals with the links between the development of new drugs, and particularly of innovative new drugs, and the international activities of U.S. drug companies. While U.S.
Benjamin I. Cohen +2 more
core
Protective effect of carnosic acid against acrylamide-induced toxicity in RPE cells [PDF]
Albalawi, Aishah Eis S +4 more
core +1 more source
Particles from preformed polymers as carriers for drug delivery [PDF]
Biodegradable and biocompatible polymers are widely used for the encapsulation of drug molecules. Various particulate carriers with different sizes and characteristics have been prepared by miscellaneous techniques.
Elaissari, A. +5 more
core
Impact of insufficient drug efficacy of antiparkinson agents on patient's quality of life: a cross-sectional study. [PDF]
Tsugawa J +5 more
europepmc +1 more source
Fall Risk Increasing Drugs: The Effect on Injuries of the Frail Elderly Estimated from Administrative Data [PDF]
Society benefits on a large scale from improved medical care and pharmaceuticals. The prescription of pharmaceuticals, however, also carries risks such as the possibility of an increased risk of falls, which may lead to severe injuries and increased ...
Ahrens, Susanne +5 more
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