Results 11 to 20 of about 3,714 (189)
Long-Term Adherence and Drug Utilisation Patterns Among New Users of Anti-Hyperlipidemic Monotherapy: Development of a Risk Prediction Model. [PDF]
J Eval Clin PractABSTRACT Rationale Real‐world long‐term adherence and drug patterns are essential in hyperlipidemia management. However, the evidence was unclear. Aims and Objectives This study aimed to assess long‐term adherence, drug usage patterns of anti‐hyperlipidemic monotherapy, associated risk factors, and develop risk prediction models. Methods We performed a
Li X +4 more
europepmc +2 more sources
British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3596-3605, December 2023., 2023 Aims Limiting use of the antidepressant dosulepin has been encouraged due to associated risks of toxicity. In April 2011, the All Wales Medicines Strategy Group introduced a National Prescribing Indicator (NPI) to monitor dosulepin usage. The aim of this study was to investigate antidepressant prescribing patterns, and selected adverse events in ...
Katherine Chaplin +4 more
wiley +1 more source
Drug Repurposing Investigation for Combating Ebola Virus Disease: Database Mining, Docking Calculations, Molecular Dynamics, and Density Functional Theory Study. [PDF]
ChemistryOpenDrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Abdelrahman AHM +5 more
europepmc +2 more sources
British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3715-3752, December 2023., 2023 Aims Certain combinations of medications can be harmful and may lead to serious adverse drug events (ADEs). Identifying potentially problematic medication clusters could help guide prescribing and/or deprescribing decisions in hospital. The aim of this study is to characterize medication prescribing patterns at hospital discharge and determine which ...
Daniala L. Weir +7 more
wiley +1 more source
Velvet bean (Mucuna pruriens): A sustainable protein source for tomorrow
Legume Science, Volume 5, Issue 3, September 2023., 2023 Abstract Protein is one of the essential major nutrients required for the cell functioning in human body. Complete proteins, which are usually found in animal‐based proteins, despite of having high biovailability also cause adverse effect on the environment and increased the risk of diet‐related chronic diseases.
Chinju Baby +3 more
wiley +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 2, Issue 3, September 2023., 2023 Abstract Aim Understanding the appropriate prescription of psychotropics for hospitalized patients in terms of preventing falls is an important issue. The aim of this study was to assess the associations between the occurrence of falls and the use of various individual psychotropics in hospitalized patients. Methods A retrospective matched case–control
Chihiro Morishita +11 more
wiley +1 more source
Sustained Release Antiparkinson Agents: Controlled Release Levodopa [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1992 ABSTRACT:The rationale for sustained release oral levodopa preparations is to deliver levodopa in the areas of maximal intestinal absorption in a slow and predictable way, leading to stable plasma levodopa levels and brain dopamine levels, therefore resulting in a lengthened duration of action.
S, Gauthier, D, Amyot
openaire +2 more sources
Prescription rate of medications potentially contributing to lower urinary tract symptoms and detection of adverse reactions by prescription sequence symmetry analysis [PDF]
, 2015 BACKGROUND: The lower urinary tract symptoms (LUTS) increases with age and can have a significant effect on the quality of life of the patients. Elderly patients, who are often characterized by a decline in physiological functional and polypharmacy, are ...
Fumihiko Ando +5 more
core +2 more sources
Anticonvulsant Activity of Antiparkinsonism Agents
Experimental Biology and Medicine, 1968 SummaryThe anticonvulsant activity of synthetic antiparkinsonism agents has been studied in mice with experimental seizures and in children with myoclonic spasms refractory to conventional medications. Procyclidine and trihexyphenidyl protected mice from maximal electroshock seizures.
J G, Millichap +2 more
openaire +2 more sources
Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
, 2010 Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
core +1 more source