Results 111 to 120 of about 63,333 (299)
Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background DaxibotulinumtoxinA (DAXI), a novel botulinum neurotoxin (BoNT) formulation, was shown to be safe, effective, and long‐lasting in the treatment of cervical dystonia (CD) over one treatment cycle in the phase 3, randomized, placebo‐controlled ASPEN‐1 trial.
Peter McAllister +11 more
wiley +1 more source
Role of mitochondria in Parkinson disease [PDF]
, 1999 The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remained largely unknown. Exceptions include rare missense mutations in the alpha-synuclein gene on chromosome 4, a potentially pathogenic mutation affecting ...
Graeber, M. B. +4 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well‐established therapy in advanced Parkinson's disease (PD) improving motor and non‐motor signs including sleep. The mechanisms of sleep improvement are insufficiently understood.
Julia Steinhardt +6 more
wiley +1 more source
Laserlight visual cueing device for freezing of gait in Parkinson's disease: a case study of the biomechanics involved [PDF]
, 2015 Background: Freezing of gait (FOG) is a serious gait disorder affecting up to two-thirds of people with Parkinson's disease (PD). Cueing has been explored as a method of generating motor execution using visual transverse lines on the floor.
B. Evans +7 more
core +1 more source
Evaluation of Nonmotor Symptoms in Diagnosis of Parkinsonism and Tremor
Parkinson's Disease, 2016 Background. Nonmotor symptoms particularly olfactory dysfunction, RBD, depression, hallucinations, and constipation are currently not included in the typical clinical criteria for diagnosing Lewy body Parkinsonian disorders (LBPD).
Andrew H. Evans, Chiun-Hian Chai
doaj +1 more source
Parkinsonian motor impairment predicts personality domains related to genetic risk and treatment outcomes in schizophrenia [PDF]
, 2017 Identifying endophenotypes of schizophrenia is of critical importance and has profound implications on clinical practice. Here we propose an innovative approach to clarify the mechanims through which temperament and character deviance relates to risk for
Alemán, Gabriela González +15 more
core +2 more sources
Tremor in motor neuron disease may be central rather than peripheral in origin [PDF]
, 2018 BACKGROUND AND PURPOSE: Motor neuron disease (MND) refers to a spectrum of degenerative diseases affecting motor neurons. Recent clinical and post-mortem observations have revealed considerable variability in the phenotype.
Balint, B +9 more
core +2 more sources
Pleiotropy and the Increasing Complexity of Parkinson's Disease Genetics
Annals of Neurology, EarlyView.
Jonggeol Kim, Joshua M. Shulman
wiley +1 more source
Micrographia in Parkinson's Disease: Automatic Recognition through Artificial Intelligence
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) leads to handwriting abnormalities primarily characterized by micrographia. Whether micrographia manifests early in PD, worsens throughout the disease, and lastly responds to L‐Dopa is still under scientific debate.
Francesco Asci +8 more
wiley +1 more source
Neuropsychiatric symptoms and PET imaging characteristics in patients with Parkinson-plus syndromes
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 Objective To explore the neuropsychiatric symptoms and 18F-fluoro-2-deoxy-D-glucose (18F-FDG) PET imaging features of Parkinson-plus syndromes. Methods There were 8 patients with probable Parkinson-plus syndromes, including one case of multiple ...
Miao ZHANG +4 more
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