Results 261 to 270 of about 65,159 (298)

Aesculus hippocastanum Extract Exerts Neuroprotective Effects in an MPP+‐Induced Parkinson's Disease Model via PPARγ Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by the loss of dopaminergic neurons in the substantia nigra. In this study, we investigated the neuroprotective and anti‐inflammatory potential of Aesculus hippocastanum (horse chestnut extract, HCE) in an in vitro model of PD.
Sarah Adriana Scuderi, Alessio Ardizzone, Giovanna Casili, Deborah Mannino, Antonio Catalfamo, Marika Lanza, Emanuela Esposito   +6 more
wiley   +1 more source

Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Extracellular vesicles (EVs) are tiny, membrane‐covered packets that cells naturally release to send molecular information to one another. In the brain, they function as couriers that move proteins, lipids, and other signals between neurons, glial cells, and the blood–brain barrier.
Berenice N. Bernal‐Vicente, Isaac Ponce, Emmanuel Ríos‐Castro, Perla Moreno‐Castilla, Luis B. Tovar‐y‐Romo   +4 more
wiley   +1 more source

Utility of susceptibility-weighted imaging in Parkinson's disease and atypical Parkinsonian disorders. [PDF]

Transl Neurodegener, 2016
Wang Z, Luo XG, Gao C.
europepmc   +1 more source

Synergistic Effects of Levodopa, Benserazide, and Nortriptyline on Behavioral Impairments and Brain Pathology in an Experimental Rat Model of Parkinson’s Disease

Neurology Research International, Volume 2026, Issue 1, 2026.
Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). In addition to postural instability, rigidity, tremor, and bradykinesia, patients will experience depression and/or anxiety at any time during PD.
Maryam Ezzedin, Sam Zarbakhsh, Houman Parsaei, Ali Ghanbari, Abbas Ali Vafaei, Zohre Mohsenvand, Seyed Ali Seyedinia, Parnia Tarahomi, Manouchehr Safari, Rita Chiaramonte   +9 more
wiley   +1 more source

Fatigue‐Inducing Protocols in Parkinson’s Disease: Implications for Gait Assessment and Rehabilitation: A Systematic Review

Parkinson's Disease, Volume 2026, Issue 1, 2026.
Background Fatigue is a common and disabling nonmotor symptom of Parkinson’s disease (PD), which significantly impacts gait and overall mobility. In spite of its clinical significance, the biomechanical consequences of different fatigue induction protocols on gait performance in PD are not yet well understood. Objective To systematically review fatigue
Mahdi Majlesi, Elaheh Azadian, Nader Farahpour, Rezvan Bakhtiarian, Hadi Nobari, Cristine Alves da Costa   +5 more
wiley   +1 more source

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Atypical Parkinsonian Disorders

Movement Disorders, 2005
In many neurological diseases the topography of the lesion, whatever its nature, determines the clinical signs, whereas the nature of the lesion (vascular, inflammatory, degenerative, etc.) whatever its topography, determines the time course. According to J. P. Martin (1), this general principle cannot be simply applied to diseases of the basal ganglia
Gregor K. Wenning, Werner Poewe
  +4 more sources

Neuroimaging in Parkinsonian Disorders

Neurology India, 2018
Neuroimaging (NI) in Parkinson's disease (PD) includes functional techniques like positron emission tomography (PET) and single photon emission computed tomography (SPECT), and morphological imaging using magnetic resonance imaging (MRI) and transcranial sonography to probe different aspects of the neurobiology of PD.
Madhavi, Tripathi, Atin, Kumar, Chandrasekhar, Bal   +2 more
openaire   +2 more sources

Atypical Parkinsonian Disorders

Neurologic Clinics
Atypical parkinsonian disorders (APD) include progressive supranuclear palsy, corticobasal degeneration, and multiple system atrophy. Identifying APD is important because they have different pathogenesis, disease course, and prognosis than Parkinson's disease (PD), and require different treatments.
Nahid, Olfati, Fahimeh H, Akhoundi, Irene, Litvan   +2 more
openaire   +2 more sources

Serial volumetric MRI in Parkinsonian disorders

Movement Disorders, 2009
AbstractTracking progression in neurodegenerative diseases is hampered by the limitations of the clinical rating scales, which are seldom linear, suffer from floor and ceiling effects, lack the ability to distinguish symptomatic change from disease modification, and are limited by imperfect intra‐ and inter‐rater reliability.
Wild, E.J., Fox, N.C.I.
openaire   +4 more sources

ATYPICAL PARKINSONIAN DISORDERS

Continuum, 2004
Atypical Parkinsonian disorders , Atypical Parkinsonian disorders , کتابخانه دیجیتال جندی شاپور ...
openaire   +1 more source