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Atypical Parkinsonian Disorders
Neurologic ClinicsAtypical parkinsonian disorders (APD) include progressive supranuclear palsy, corticobasal degeneration, and multiple system atrophy. Identifying APD is important because they have different pathogenesis, disease course, and prognosis than Parkinson's disease (PD), and require different treatments.
Nahid, Olfati +2 more
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Serial volumetric MRI in Parkinsonian disorders
Movement Disorders, 2009AbstractTracking progression in neurodegenerative diseases is hampered by the limitations of the clinical rating scales, which are seldom linear, suffer from floor and ceiling effects, lack the ability to distinguish symptomatic change from disease modification, and are limited by imperfect intra‐ and inter‐rater reliability.
Wild, E.J., Fox, N.C.I.
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The Role of Tau Imaging in Parkinsonian Disorders
Current Neurology and Neuroscience Reports, 2018Differential diagnosis of atypical Parkinson syndromes (APS) is difficult as clinical presentations may vary and as there is a strong overlap between disease entities. Aggregations of misfolded and hyperphosphorylated tau proteins are the common denominator of many of these diseases.Several tau targeting positron emission tomography (PET) tracers have ...
Hammes, Jochen +2 more
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Glabellar and palmomental reflexes in parkinsonian disorders
Neurology, 2004The authors examined the glabellar reflex and the palmomental reflex in 100 subjects, including patients with Parkinson disease (n = 41), patients with progressive supranuclear palsy (n = 12), patients with multiple system atrophy (n = 7), and healthy, age-matched, controls (n = 40).
Harris Brodsky +3 more
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Brain perfusion differences in Parkinsonian disorders
Movement Disorders, 2011AbstractWe aimed to objectively examine the brain perfusion differences between PD, Parkinson variant of multiple system atrophy, and progressive supranuclear palsy. 99mTc ethylcysteinate dimer single‐photon emission CT (SPECT) was performed in 28 patients with PD, 12 with Parkinson variant of multiple system atrophy, 19 with progressive supranuclear ...
Yusuke Hazama +7 more
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ATYPICAL PARKINSONIAN DISORDERS
Continuum, 2004Atypical Parkinsonian disorders , Atypical Parkinsonian disorders , کتابخانه دیجیتال جندی شاپور ...
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The auditory startle reaction in parkinsonian disorders
Movement Disorders, 2001The auditory startle reaction to an unexpected loud stimulus is regarded as a brainstem reflex originating in the nucleus reticularis pontis caudalis and being distributed up the brainstem and down the spinal cord along slowly conducting pathways. Auditory startle responses (ASR) have been reported absent or reduced in progressive supranuclear palsy ...
Markus Kofler +8 more
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Update of atypical parkinsonian disorders
Current Opinion in Neurology, 2007This timely update discusses novel diagnostic approaches, recently identified genes, and innovative experimental symptomatic treatments for these devastating disorders.Differential patterns in the basal ganglia transcranial sonography, magnetic resonance diffusion-weighted imaging regional apparent diffusion coefficients in the brainstem, basal ganglia
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Tracking the neurodegeneration of parkinsonian disorders – a pilot study
Neuroradiology, 2007The purpose of the study was to explore the possibilities of using diffusion tensor imaging (DTI) and tractography (DTT) for the differential diagnosis and monitoring of disease progression in idiopathic Parkinson's disease (IPD), compared with the atypical parkinsonian disorders multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). A
Nilsson, C +5 more
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Cerebrospinal Fluid Levels of Neurogranin in Parkinsonian Disorders
Movement Disorders, 2019AbstractBackgroundCSF concentration of neurogranin has been suggested as a biomarker for synapse dysfunction.ObjectivesTo investigate CSF neurogranin in parkinsonian disorders compared to controls and Alzheimer's disease and the possible correlations between neurogranin and cognitive and motor impairment.MethodsWe included 157 patients with PD, 29 with
Henrik Zetterberg +8 more
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