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Neuropathology of Atypical Parkinsonian Disorders [PDF]
, 2005 Although the clinical syndrome of parkinsonism (rigidity, bradykinesia, and tremor) is most often owing to idiopathic Parkinson’s disease (PD), it may also be associated with a variety of other underlying pathologies (Table 1) (1, 2, 3). Each of these other pathological conditions tends to have a characteristic clinical phenotype, however atypical ...
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Progression of falls in postmortem-confirmed Parkinsonian disorders
Movement Disorders, 1999Although falls are known to occur in several parkinsonian disorders, such as Parkinson's disease (PD), multiple system atrophy (MSA), dementia with Lewy bodies (DLB), corticobasal degeneration (CBD), and progressive supranuclear palsy (PSP), differences in the evolution of this feature have not been studied systematically in pathologically confirmed ...
Wenning, Gregor K. +7 more
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Parkinsonian Disorders in Clinical Practice
2009This book gives the reader an up-to-date, clear and logical idea of what caring for parkinsonian patients entails - a challenge that clinicians will face for ...
Andreas Hartmann +2 more
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What is an Atypical Parkinsonian Disorder? [PDF]
, 2005 A parkinsonism is a syndrome defined by akinesia associated with rigidity or rest tremor. The akinesia can be expressed as motor slowness (bradykinesia) or as a paucity of movement (hypokinesia), i.e., difficulty in the initiation of or decreased amplitude of movements such as arm swing or facial expression.
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Hand, foot, and spine deformities in parkinsonian disorders
Journal of Neural Transmission, 2019Hand and foot deformities, known as "striatal deformities", and other musculoskeletal abnormalities such as dropped head, bent spine, camptocormia, scoliosis and Pisa syndrome, are poorly understood and often misdiagnosed features of Parkinson's disease and other parkinsonian syndromes. These deformities share some similarities with known rheumatologic
Joseph Jankovic, Subhashie Wijemanne
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Recent advances in atypical parkinsonian disorders
Current Opinion in Neurology, 1999Recent advances in epidemiologic, diagnostic, pathologic, and management aspects of atypical parkinsonian disorders are reviewed and placed in perspective. The implications of considering progressive supranuclear palsy and corticobasal degeneration as tauopathies, and multiple system atrophy and dementia with Lewy bodies as alpha-synucleopathies are ...
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Caribbean parkinsonism and other atypical Parkinsonian disorders
Parkinsonism & Related Disorders, 2004Atypical parkinsonism (AP) is a term applied to disorders characterized by parkinsonism that evolves rapidly, with poor or transient response to levodopa, or has other associated features such as early falls and postural instability, early autonomic failure, supranuclear gaze palsy, pyramidal or cerebellar signs, alien hand syndrome or severe ideomotor
Daniela Calandrella +2 more
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Disorders of Intention in Parkinsonian Syndromes
2003In recent years, the symptom of akinesia in parkinsonism has provided a valuable window into the physiological substrate of voluntary movement in man, particularly the role of the basal ganglia and the influence of dopamine. In a similar way, the study of individual nonmotor symptoms in parkinsonism can provide insights into the subsystems underlying ...
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Applause sign in parkinsonian disorders and Huntington's disease
Movement Disorders, 2008AbstractThe applause sign has been previously reported to be indicative of neurodegenerative disorders, such as progressive supranuclear palsy (PSP). In order to determine the sensitivity, specificity, and positive predictive value, we tested it in patients with PSP, Parkinson's disease (PD), multiple system atrophy (MSA), corticobasal degeneration ...
Laura J.C. Wu +3 more
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Pathophysiology and Treatment of Orthostatic Hypotension in Parkinsonian Disorders
Current Treatment Options in Neurology, 2016Orthostatic hypotension (OH) is defined as a sustained pathological reduction in blood pressure within 3 min after orthostatic stress such as tilt-table testing or active standing. Non-neurogenic OH is caused by either decreased cardiac output or impaired vasoconstriction without a primary autonomic disorder whereas neurogenic OH results from ...
Christopher H. Gibbons, Dong In Sinn
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