Results 191 to 200 of about 151,540 (363)

Unveiling Parkinson's Disease-like Changes Triggered by Spaceflight [PDF]

open access: yesarXiv
A meta-analysis of spaceflight data from both mouse and human flights reveals a striking overlap with Parkinson's disease (PD). Parallels include: changes in gait, loss of dopamine, sustained changes in the basal ganglia, loss of tyrosine hydroxylase in the substantia nigra, and systemic mitochondrial dysfunction.
arxiv  

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi   +11 more
wiley   +1 more source

Parkinsonism [PDF]

open access: yes, 2011
Anna DePold Hohler, Marcus Ponce de Leon
openaire   +1 more source

Parkinsons sykdom og parkinsonisme [PDF]

open access: yesTidsskrift for Den norske legeforening, 2017
Lasse Pihlstrøm, Kashif Waqar Faiz
openaire   +2 more sources

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

MEA‐seqX: High‐Resolution Profiling of Large‐Scale Electrophysiological and Transcriptional Network Dynamics

open access: yesAdvanced Science, EarlyView.
How can we fully understand brain function and disease without uncovering the causal coordination between molecular and neural activity across space and time? MEA‐seqX tackles this challenge by integrating advanced electrophysiology, spatial transcriptomics, and artificial intelligence predictions, revealing multiscale dynamics.
Brett Addison Emery   +9 more
wiley   +1 more source

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