Results 191 to 200 of about 109,533 (316)
DNAJC12 Disease: Clinical Spectrum and Long-Term Outcomes. [PDF]
Neurol GenetManti F, Ricciardi G, Nardecchia F, Tolve M, Artiola C, Carbone MT, Carducci C, Mei D, Porta F, Ortolano R, Candela E, Burlina A, Guerrini R, Pisani F, Angeloni A, Leuzzi V. +15 moreeuropepmc +1 more sourceBrd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway
Advanced Science, EarlyView.MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.Chenxiao Li, Xiaochen Zhang, Jiangwei Xia, Shuang Liu, Yushan Du, Sihan Li, Shukui Zhang, Yong Zhang, Fen Ji, Jianwei Jiao, Jingjing Zhang +10 morewiley +1 more sourceArgyrophilic grain disease: epidemiology and association with cognitive decline and parkinsonism. [PDF]
Brain CommunArakawa A, Matsubara T, Shioya A, Hara M, Hiroyoshi Y, Kurihara M, Morimoto S, Kato T, Higashihara M, Sengoku R, Kameyama M, Kanemaru K, Tokumaru AM, Arai T, Hara N, Miyashita A, Ikeuchi T, Tarutani A, Hasegawa M, Iwata A, Toda T, Murayama S, Saito Y. +22 moreeuropepmc +1 more sourceNeuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism
Advanced Science, EarlyView.Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen +12 morewiley +1 more sourceCorrigendum to "Examining balance and the likelihood of falls in Huntington's disease". [Clin. Parkinsonism Relat. Dis. 13 (2025) 100399]. [PDF]
Clin Park Relat DisordYouhanan N, Kaur J, Hall A, Bagga K, Patel S, Sidhu A, Alskaf R, Shaik Z, Gilbert PE, Goble DJ, Corey-Bloom J. +10 moreeuropepmc +1 more sourceOral Cannabidiol for Seborrheic Dermatitis in Patients With Parkinson Disease: Randomized Clinical Trial
Isaac Weber, Caterina Zagona‐Prizio, Torunn E Sivesind, Madeline Adelman, Mindy D Szeto, Ying Liu, Stefan Sillau, Jacquelyn Bainbridge, Jost Klawitter, Cristina Sempio, Cory A. Dunnick, Maureen A. Leehey, Robert P. Dellavalle +12 moreopenalex +1 more sourceAlternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease
Advanced Science, EarlyView.In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu +17 morewiley +1 more sourceRAB3A variants in ataxia and other neurodegenerative disorders. [PDF]
BrainPercetti M, Monfrini E, Del Bo R, Canesi M, Cavallieri F, Di Rauso G, Fioravanti V, Del Prete E, Frosini D, Palermo G, Ceravolo R, Sacilotto G, Di Fonzo A. +12 moreeuropepmc +1 more source
