Results 191 to 200 of about 435,882 (385)
Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Advanced Science, EarlyView.Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin +9 more
wiley +1 more source
Estúdio crítico sobre la operación de Cooper (ligadura de la artéria coroidea anterior) en la enfermedad de Parkinson [PDF]
, 1955 Raul. F. Matera +2 more
openalex +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Advanced Science, EarlyView.Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia +29 more
wiley +1 more source
JAMES PARKINSON (1755–1824). Edited by Macdonald Critchley. London: Macmillan & Co. 1955. Pp. 268 + xvi. 15s [PDF]
, 1957 George Gordon
openalex +1 more source
Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]
, 2018 Benitez, Bruno A +11 more
core +2 more sources
Advanced Science, EarlyView.This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao +17 more
wiley +1 more source
Editorial: Neuroimaging in Parkinson's disease and Parkinsonism
Frontiers in Neurology, 2023 Yu Zhang +3 more
openaire +3 more sources
Advanced Science, EarlyView.This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing +18 more
wiley +1 more source
Prevalence of Parkinson’s disease and other types of Parkinsonism in Al Kharga district, Egypt
Neuropsychiatric Disease and Treatment, 2013 Hamdy N El-Tallawy,1 Wafaa M Farghaly,1 Ghaydaa A Shehata,1 Tarek A Rageh,1 Nabil M Abdel Hakeem,2 Mohamed Abd Al Hamed,1 Reda Badry1 1Department of Neurology, Assiut University, 2Al-Azhar University – Assiut branch, Assiut, Egypt Abstract ...
El-Tallawy HN +6 more
doaj