RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Understanding wetland park feature influence through cross-regional multimodal analysis and interpretable modeling. [PDF]
Zheng X, Huang Y, Xie Z, Zheng A.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Empirical analysis of the carbon-economy nexus in industrial parks using an integrated decoupling-decomposition framework from a major industrial region. [PDF]
Zhu Q +6 more
europepmc +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Tick Infestation Among Stray Dogs of Urban Chișinău, Moldova: Species Distribution and Pathogen Detection. [PDF]
Morozov A +3 more
europepmc +1 more source
Towards a unified theory of false memory for similar episodes. [PDF]
Parks CM, Yonelinas AP, Wahlheim CN.
europepmc +1 more source
Parasitological survey of <i>Toxocara canis</i> and <i>Ancylostoma caninum</i> in Puno urban parks (3825 m): Evidence of larval development under Andean conditions. [PDF]
Castillo DDR, Gutiérrez ÁC.
europepmc +1 more source
Living on the Edge: Juvenile Foraging and Adult Breeding Ecology of an Aerial Top Predator in Urban Environments. [PDF]
Engler M, Krone O.
europepmc +1 more source
Green urban environments enhance brain-to-brain synchrony. [PDF]
Kerimova N +5 more
europepmc +1 more source

