Results 81 to 90 of about 316,530 (280)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Santiago 1910: Tramas del ocio
A inicios del s. XX la consolidación de una nueva espacialidad urbana y el reconocimiento de hitos geográficos como espacios públicos genera una nueva forma de concebir la ciudad.
José Rosas +3 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Peri-Urban and Urban Green Space Management and Planning: The Case of Thessaloniki, Greece
With the increase in population and commercial development, urban development has led to a decrease in natural vegetation and an increase in solid surfaces, which negatively affect the environment.
Maria Baxevani +4 more
doaj +1 more source
Innovative platforms of Russia – "good and various" (structural analysis) Part 2
This article completes the analysis started by the authors in the previous issue on the development of Russian innovation platforms (primarily industrial parks), which are expected to become “points of growth”, able to provide a decisive impetus to the ...
Natalia V. Latova, Yuryi V. Latov
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
This study, based on the perspective of supply and demand coupling between parks and living circles, divides spatial units by introducing the Thiessen polygon method with urban parks as the core. Simultaneously, the coefficient of variation (CV) was used
Chenpei Wang +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

