Results 81 to 90 of about 316,530 (280)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Santiago 1910: Tramas del ocio

open access: yesARQ, 2010
A inicios del s. XX la consolidación de una nueva espacialidad urbana y el reconocimiento de hitos geográficos como espacios públicos genera una nueva forma de concebir la ciudad.
José Rosas   +3 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Peri-Urban and Urban Green Space Management and Planning: The Case of Thessaloniki, Greece

open access: yesLand
With the increase in population and commercial development, urban development has led to a decrease in natural vegetation and an increase in solid surfaces, which negatively affect the environment.
Maria Baxevani   +4 more
doaj   +1 more source

Innovative platforms of Russia – "good and various" (structural analysis) Part 2

open access: yesСоциологическая наука и социальная практика, 2016
This article completes the analysis started by the authors in the previous issue on the development of Russian innovation platforms (primarily industrial parks), which are expected to become “points of growth”, able to provide a decisive impetus to the ...
Natalia V. Latova, Yuryi V. Latov
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Evaluation and Division Methods of Coupled Spatial Units between Parks and Living Circles: A Case Study of Four National-Level New Areas

open access: yesBuildings
This study, based on the perspective of supply and demand coupling between parks and living circles, divides spatial units by introducing the Thiessen polygon method with urban parks as the core. Simultaneously, the coefficient of variation (CV) was used
Chenpei Wang   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Park the Parking

open access: yesJCO Oncology Practice, 2020
Naveen, Premnath   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy