Results 101 to 110 of about 891,705 (311)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

"International Parliament Organs and European Institutional Organisation: The Case of the European Parliament" [PDF]

open access: yes, 1995
The European Parliament is a member of the family of international parliamentary organs (lPOs). "Parts of international organisations, composed of parliamentarians", as they are often described, are in my view one of the most important achievements of ...
Sabic, Zlatko.
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

The Long Road to Uluru and Beyond [PDF]

open access: yes, 2019
This paper explores the significance of the Uluru Statement from The Heart and its place in the post settlement Indigenous journey. It is also relevant to the nation’s journey towards reconciliation.
Carne, Greg, Chaney, Fred
core   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Problems of a Subject and Object of Criminal Attack on Persons or Establishments that are under the International Protection by the Criminal Code of the Kyrgyz Republic

open access: yesЕвразийская интеграция: экономика, право, политика, 2019
The article deals with questions of correlation of the international criminal law and the criminal legislation of the Kyrgyz Republic and issues of a subject and object of criminal attack on the persons or establishments using international protection ...
C. Aidarbekov
doaj  

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