Results 91 to 100 of about 288,785 (278)

Marking the card : the Scottish Parliament at 1000 days [PDF]

, 2002
Paper presented to the IBIS conference Renovation or revolution? new territorial politics in Ireland and the United Kingdom, University College Dublin, 3 April 2002.The first term of the Scottish Parliament is more than half-way to completion, with ...
McCrone, David
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The 43rd Parliament: traits and trends [PDF]

, 2013
Drawing on the statistical tables featured in the 32nd edition of the Parliamentary Handbook, this paper examines the biographical details of the senators and members of Australia\u27s 43rd Parliament.IntroductionIn recent years, academics and media ...
Martin Lumb
core  

Book Review: Lobbying the European Union: Institutions, Actors and Issues, David Coen and Jeremy Richardson (eds.) [PDF]

Romanian Journal of European Affairs, 2013
The volume “Lobbying the European Union: Institutions, Actors and Issues”, collects 16 articles on interest group politics at EU level, focusing on the main elements of European lobbying – the existing relations between the EU institutions and the ...
Alexandra Pop
doaj  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Indexes to Debates of the House of Assembly (Hansard) [PDF]

, 1961
Merged with: Debates of the House of Delegates, and; Debates of the House of Representatives, to form: Debates of Parliament. 1st Session, 1st Parliament, vol.
South Africa Parliament
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Problems of a Subject and Object of Criminal Attack on Persons or Establishments that are under the International Protection by the Criminal Code of the Kyrgyz Republic

Евразийская интеграция: экономика, право, политика, 2019
The article deals with questions of correlation of the international criminal law and the criminal legislation of the Kyrgyz Republic and issues of a subject and object of criminal attack on the persons or establishments using international protection ...
C. Aidarbekov
doaj