Results 101 to 110 of about 214,501 (284)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Public administration of safety of navigation: multi-level challenges and answers

open access: yesLex Portus, 2020
The article addresses the advantages and shortcomings of multi-level system of ensuring safety of navigation. The principle of the navigation safety is considered as fundamental determinant of changes in maritime laws and regulations at the international,
Tetiana Plachkova, Oleksandr Avdieiev
doaj   +1 more source

League of Nations : correspondence with His Majesty's Government concerning the protocol for the pacific settlement of international disputes.

open access: yes, 1925
Cover title.; At head of title: 1925. The Parliament of the Commonwealth of Australia.; Electronic reproduction. Canberra, A.C.T.
Australia. Parliament.
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Indexes to Debates of the House of Assembly (Hansard)

open access: yes, 1974
Debates of Standing Committees published annually and parallel with Afrikaans title. 139 v. 22 cm. J 705.K2.S62South Africa Parliament House of Assembly. Debates of Standing Committees published.
South Africa Parliament
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Consensus and the Proportionality of Office Distribution in the European Parliament, 1994-2007 [PDF]

open access: yes, 2007
Consensus is embedded in the European Parliament. One of its forms is in the proportionality that applies between political groups in the distribution of office positions, such as Committee Chairman or Bureau members, that affect policy outcomes ...
Benedetto, Giacomo.
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

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