Results 71 to 80 of about 72,996 (238)

Book Review: Lobbying the European Union: Institutions, Actors and Issues, David Coen and Jeremy Richardson (eds.) [PDF]

open access: yesRomanian Journal of European Affairs, 2013
The volume “Lobbying the European Union: Institutions, Actors and Issues”, collects 16 articles on interest group politics at EU level, focusing on the main elements of European lobbying – the existing relations between the EU institutions and the ...
Alexandra Pop
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Problems of a Subject and Object of Criminal Attack on Persons or Establishments that are under the International Protection by the Criminal Code of the Kyrgyz Republic

open access: yesЕвразийская интеграция: экономика, право, политика, 2019
The article deals with questions of correlation of the international criminal law and the criminal legislation of the Kyrgyz Republic and issues of a subject and object of criminal attack on the persons or establishments using international protection ...
C. Aidarbekov
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

China’s global governance strategy and the revival of leftist ideologies in Africa: a constructivist analysis of norm diffusion and political alignment

open access: yesCogent Social Sciences
This empirical and theoretical study examines China’s strategic engagement in Africa through a constructivist lens, analyzing how Beijing’s approach to global governance influences the resurgence of leftist ideologies across the continent.
Jani Grey Kasunda
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

HUMAN SECURITY AGENDA- IDEOLOGICAL BASIS AND DEVELOPMENT IN THE CONTEXT OF CANADIAN FOREIGN POLICY

open access: yesPravo, 2016
In accordance with the bases of liberal internationalism, the political moral community can be extended beyond the boundaries of the national state. The presence of the moral dimension is inherent to foreign policy, including a foreign political agenda ...
Dragan Božović
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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