Results 51 to 60 of about 286,053 (260)

European Parliament diplomacy and the end of the Cold War : the integration of central and eastern European countries [PDF]

open access: yes
Published online: 30 April 2025The European Parliament played a fundamental role in reshaping the political landscape of central and eastern Europe during and after the end of the Cold War, setting out an agenda for European enlargement and ...
ANGHEL, Veronica
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Union of South Africa. Debates of the House of Assembly. Fourth Session Fourth Parliament 1924 [PDF]

open access: yes, 1924
Fourth Session, 4th Parliament, vol. 1 (25 Jan.-10 Apr. 1924)-4th Session, 12th Parliament, v. 108 (1 May-26 May 1961). Vol. 1 of this series published parallel with the Dutch title: Debatten van de Volksraad.Debates of the House of Assembly of the ...
South Africa Parliament
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The 43rd Parliament: traits and trends [PDF]

open access: yes, 2013
Drawing on the statistical tables featured in the 32nd edition of the Parliamentary Handbook, this paper examines the biographical details of the senators and members of Australia\u27s 43rd Parliament.IntroductionIn recent years, academics and media ...
Martin Lumb
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Practical implementation of CRD III remuneration rules in the UK - issues and results [PDF]

open access: yes, 2012
Professor Kern Alexander's report on the UK's regulation of banker's bonuses to the European Parliament on 30 January 2012. In the report, he argues for amending the EU Capital Requirements Directive's (CRD III) prescriptive approach for regulating ...
Alexander, Kern
core   +1 more source

Příspěvek k jubileu Bedřicha Moldana

open access: yesEnvigogika
Jen pokud dokážeme pečovat o naši planetu, vytvoříme stabilní základ pro růst a rozvoj společnosti. Profesor Bedřich Moldan byl jedním z těch, kdo tuto skutečnost dokázali srozumitelně a přesvědčivě přinášet do veřejné debaty i politického rozhodování.
Luděk Niedermayer
doaj   +1 more source

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