Results 161 to 170 of about 913,370 (314)
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad+8 more
wiley +1 more source
A DESCRIPTION OF THE COFFRE DAM AT THE SITE FOR THE NEW HOUSES OF PARLIAMENT. [PDF]
Gail Dalrymple
openalex +1 more source
Choosing the electoral system: why not simply the best one? [PDF]
The paper illustrates a simple empirical rule to choose the best electoral system for a Parliament.
Ortona, Guido
core
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang+11 more
wiley +1 more source
A Validated Model to Predict Severe Weight Loss in Amyotrophic Lateral Sclerosis
ABSTRACT Severe weight loss in amyotrophic lateral sclerosis (ALS) is common, multifactorial, and associated with shortened survival. Using longitudinal weight data from over 6000 patients with ALS across three cohorts, we built an accelerated failure time model to predict the risk of future severe (≥ 10%) weight loss using five single‐timepoint ...
David G. Lester+4 more
wiley +1 more source
COOPERATIVES AND INVESTOR OWNED FIRMS: DO THEY MARCH TO THE SAME DRUMMER? [PDF]
Agribusiness,
Fulton, Joan R.+2 more
core +1 more source
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji+11 more
wiley +1 more source
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi+4 more
wiley +1 more source
Finnish parliamentary speeches dataset. [PDF]
Simola S, Nieminen J, Tukiainen J.
europepmc +1 more source