Results 31 to 40 of about 891,705 (311)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Outside income and moral hazard : the elusive quest for good politicians [PDF]
In most modern democracies elected officials can work in the private sector while appointed in parliament. We show that when the political and market sectors are not mutually exclusive, a trade-off arises between the quality of elected officials and ...
Gagliarducci, Stefano+2 more
core +5 more sources
National Security of Mongolia: Past, Present & Future
DOI: http://dx.doi.org/10.5564/mjia.v0i17.79 Mongolian Journal of International Affairs, No.17 2012: 12 ...
Mijeddorj Batchimeg
doaj +1 more source
Punishment of crimes is as old as society itself. In South Africa, punishment of children continues to raise complex historical debates. For example, corporal punishment has long been abolished, but with the increase on crimes committed by children ...
Chris D. Magobotiti, Charl Cilliers
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
South Africa in international perspective
Adress delivered at an economic seminar on South Africa on 20 June 1979 at Palm Springs, California, USA.
Jan S. Marais
doaj +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
U radu se analizira primjena tzv. prigovora korupcije u međunarodnim investicijskim arbitražama kojim se sve više koriste tužene države kao načinom za izbjegavanje odgovornosti. Posebice se upozorava na problem asimetričnog pristupa odgovornosti države i
Orsat Miljenić
doaj +1 more source
The political economy of the Prussian three-class franchise [PDF]
How did the Prussian three-class franchise, which politically over-represented the economic elite, affect policies? Contrary to the predominant and simplistic view that the system allowed the landed elites to capture most political rents, we find that ...
Becker, Sascha O., Hornung, Erik
core +2 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source