Results 41 to 50 of about 82,658 (284)

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan, Deng Liu, Wuhen Xu, Yang Li, Juanli Hu, Oppermann Henry, Alexander Fuchs, Rami Abou Jamra, Zhen Liu, Mei He, Yuanlu Chen, Shengnan Wu, Xiaohuan Dong, Yiqiao Chen, Pengchao Wang, Weiyue Gu, Han Jing, Yabing Tang, Ya‐Jie Wang, Xiao Mao, Neng Xiao   +20 more
wiley   +1 more source

Acupuncture versus pharmacological conversation in treatment of atrial fibrillation in a randomized controlled trial: a systemic review and meta-analysis

European Journal of Medical Research, 2022
Objective This study aimed to investigate the effect of conventional drugs combined with acupuncture therapy on the conversion of sinus rhythm in patients with atrial fibrillation.
Yibing Li, Jinming Song, Bangqi Wu, Xuhui Wang, Lin Han, Zhenzhen Han   +5 more
doaj   +1 more source

The 4q25 variant rs13143308T links risk of atrial fibrillation to defective calcium homoeostasis [PDF]

, 2019
Aims: Single nucleotide polymorphisms on chromosome 4q25 have been associated with risk of atrial fibrillation (AF) but the exiguous knowledge of the mechanistic links between these risk variants and underlying electrophysiological alterations hampers ...
Benítez Iglesias, Raúl, Gandía, Jorge, Herraiz Martínez, Adela, Jiménez Sábado, Verónica, Llach Martínez, Anna, Lozano Velasco, Estefanía, Serra Pascual, Selma A., Tarifa Lora, Carmen, Vallmitjana Lees, Alexander, Vázquez Ruiz de Castroviejo, Eduardo   +9 more
core   +2 more sources

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

Acute myocardial infarction occurring after hypertrophic obstructive cardiomyopathy with paroxysmal atrial fibrillation: a case report

Journal of International Medical Research, 2022
Atheromatous plaque rupture and coronary artery stenosis/occlusion are leading causes of acute myocardial infarction (AMI). Other reasons for AMI are frequently overlooked.
Dingfeng Fang, Jiabin Xu, Bo Bai, Haibo Chen   +3 more
doaj   +1 more source

Electrocardiographic patch devices and contemporary wireless cardiac monitoring. [PDF]

, 2015
Cardiac electrophysiologic derangements often coexist with disorders of the circulatory system. Capturing and diagnosing arrhythmias and conduction system disease may lead to a change in diagnosis, clinical management and patient outcomes.
Carlson, SK, Chang, PM, Doshi, RN, Fung, E, Grazette, LP, Huikuri, HV, Järvelin, MR, Peters, NS, Sangha, RS, Shinbane, JS   +9 more
core   +2 more sources

Clinical approach to paroxysmal atrial fibrillation [PDF]

Clinical Cardiology, 1990
AbstractIn addition to the role of the electrophysiological substrate, paroxysmal atrial fibrillation depends on the modulation of the atrial tissues by the autonomic nervous system. Experimentally, models of atrial fibrillation can be based on either adrenergic or vagal stimulations that provoke the arrhythmia by disturbing in a different way ...
openaire   +2 more sources

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Simulation of predicting atrial fibrosis in patients with paroxysmal atrial fibrillation during sinus node recovery time in optical imaging

SLAS Technology
Paroxysmal atrial fibrillation is a common arrhythmia, and its development process and prediction of the degree of atrial fibrosis are of great significance for treatment and management.
Zhisong Chen, Hongwei Liu, Xuebo Liu, Haoming Song   +3 more
doaj   +1 more source

Diagnostic values of different ECG durations in paroxysmal AF diagnosis

Annals of Noninvasive Electrocardiology, 2022
Objective To evaluate the application value of different‐duration electrocardiograms (ECGs) in paroxysmal atrial fibrillation (AF) diagnosis. Methods A total of 220 patients with paroxysmal atrial fibrillation diagnosed by 24‐h dynamic electrocardiogram ...
Qian Li, Bing Su, Juan Liu
doaj   +1 more source