Results 71 to 80 of about 86,213 (145)

DETECTION AND FOLLOW UP OF PNH CLONE BY MEASURING CD55 AND CD59 EXPRESSION ON NEUTROPHILS

Zdravniški Vestnik, 2004
Background. Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal haematopoietic stem cell disorder characterised by intravascular haemolysis, bone marrow failure and increased tendency to thrombosis.
Uroš Mlakar, Darja Žontar
doaj  

Comparative Efficacy of Complement Inhibitors in Complement Inhibitor–Naïve PNH: A Systematic Review With Supportive Exploratory Network Meta‐Analysis of Randomized Trials

eJHaem
Introduction Paroxysmal nocturnal haemoglobinuria (PNH) is an uncommon, life‐threatening disease, caused by intravascular haemolysis by the complement system.
Rehan Ishaque, Abdul Subhan Talpur, Hafiza Sidra, Huda Memon, Furqan Tarique Memon, Fawad Talat, Taha Rafiq, Supratik Rayamajhi   +7 more
doaj   +1 more source

Positive impact of eculizumab therapy on surgery for Budd- Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria and a longterm history of thrombosis

Hematology Reports, 2016
Paroxysmal nocturnal hemoglobinuria (PNH) is associated with severe end-organ damage and a high risk of thrombosis. Budd- Chiari syndrome, which develops after thrombotic occlusion of major hepatic blood vessels, is relatively common in PNH and has been ...
Silvia De-la-Iglesia, Hugo Luzardo, Angelina Lemes, Melissa Torres, Maria Teresa Gómez-Casares, Naylen Cruz, Teresa Molero   +6 more
doaj   +1 more source

Paroxysmal nocturnal haemoglobinuria type III presenting as portal and mesenteric vein thrombosis in a young girl

, 2016
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired, life-threatening haematological disorder. It is characterised by complement induced haemolytic anaemia, thrombosis and impaired bone marrow function.
Ali, Natasha, Chaudhry, Monazza, Sarwar, Shahzad   +2 more
core  

Paroxysmal nocturnal haemoglobinuria from the first case to the current complement inhibition therapies

, 2020
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare clonal disorder that affects about 1-1.5 cases per million individuals, characterised by haemolysis, peripheral blood cytopenia, bone marrow dysfunction, thrombosis, renal impairment and arterial and ...
Gembillo G., Savica V., Santoro D., Satta E., Bellinghieri G., Salvo A.   +5 more
core  

Real‐world evidence of pegcetacoplan in patients with paroxysmal nocturnal haemoglobinuria: A nationwide Italian study

In this study, we collected real-world evidence on the use of pegcetacoplan among 22 Italian patients with paroxysmal nocturnal haemoglobinuria showing suboptimal response to anti-C5 treatments eculizumab and ravulizumab.
Marzilli, Maria Antonietta, Miglino, Maurizio, Sica, Simona, Di Giacomo, Valeria, Ricco, Alessandra, Fattizzo, Bruno, Metafuni, Elisabetta, Marktel, Sarah, Leoni, Claudia, Battipaglia, Giorgia, Condorelli, Annalisa, Sau, Antonella, Iori, Anna Paola, Patriarca, Andrea, Trolese, Annarita, Oliva, Esther Natalie, Carlino, Daniela, Sanpaolo, Grazia, Brioschi, Filippo Achille, Barcellini, Wilma   +19 more
core   +2 more sources

Paroxysmal nocturnal haemoglobinuria dengan disfagia : Suatu Laporan Kasus

, 2004
Riadi Wirawan, Ema Puspadewi, Abidin Wijanarko, lndah Gianawati - Paroxysmal nocturnal haemoglobinuria with dysphagia. A case report We reported a case of a 32 year old male with diagnosis thalassaemia and dysphagia who had been hospitalized four times ...
Perpustakaan UGM, i-lib
core   +1 more source

Childhood paroxysmal nocturnal haemoglobinuria (PNH), a report of 11 cases in the Netherlands

, 2005
Paroxysmal nocturnal haemoglobinuria (PNH) is characterized by intravascular haemolysis, nocturnal haemoglobinuria, thrombotic events, serious infections and bone marrow failure.
M. Bruin, Winkel, Lizet, Bredius, RGM, Korthof, E. T., R. G. M. Bredius, M. M. van den Heuvel-Eibrink, Heuvel-Eibrink, MM van den, te Winkel, M. L., Kraker, J. de, Meeteren, AY Schouten van, Bredius, R.G., E. T. Korthof, Bredius, R. G. M., Korthof, ET, R. Tamminga, Bruin, M. de, M. L. te Winkel, Schouten-van Meeteren, A. Y. N., de Kraker, J., Bruin, M., Tamminga, R., Van den Heuvel - Eibrink, Marry, Tamminga, R, de Kraker, J, J. Kraker, Winkel, MLT, Schouten-van Meeteren, AYN, Bruin, Marrie, Winkel, M.L. te, van den Heuvel-Eibrink, M. M., van den Heuvel-Eibrink, MM, Korthof, E.T., A. Y. N. Schouten-van Meeteren, de Bruin, M   +33 more
core   +1 more source

Flow cytometric analysis of CD55 and CD59 expression on blood cells in paroxysmal nocturnal haemoglobinuria

Folia Histochemica et Cytobiologica, 2011
PNH is a rare clonal disorder of hematopoietic stem cells, therefore all blood cells lineages are involved. The main feature is an increased sensitivity of erythrocytes to complement-mediated cell lysis due to deficiency of membrane-bound GPI ...
Anna Czyz, Iwona Mozer-Lisewska, Magdalena Trybus, Ewa Mizera-Nyczak, Jan Sikora, Grzegorz Dworacki, Jan Zeromski   +6 more
doaj   +1 more source

Prevalence of Paroxysmal Nocturnal Haemoglobinuria Clone in Aplastic Anaemia: A Single Centre Study

Haematology Journal of Bangladesh
Background: Flow cytometry assay for PNH clone is a compulsory routine test for all aplastic anaemia patients. Objective: To estimate the frequency of PNH clone in aplastic anaemia.
A. Q. M. Ashraful Haque, Salmun Nahar, A. H. M. Aslam-Ul- Haque, Md. Arif-Ur- Rahman, A B M  Yunus, Tanjina Afrin, Md. Abdul  Aziz, Md. Rafiquzzaman Khan, Md. Salahuddin  Shah, Nusrat Jahan   +9 more
doaj   +1 more source