Background: Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, genetic and acquired haematologic disease that causes complement-mediated intravascular haemolytic anaemia, thrombosis and bone marrow failure.
Alexandre-Raphael Wery +5 more
doaj +1 more source
The future of complement therapeutics
Complement is both evolutionary and scientifically old. It predates the adaptive immunity by some 600 million years and was first described in 1905 by Jules Bordet and Paul Ehrlich. For the most of its, the existence complement system has been ignored by
Martin Kolev +3 more
doaj +1 more source
DETECTION AND FOLLOW UP OF PNH CLONE BY MEASURING CD55 AND CD59 EXPRESSION ON NEUTROPHILS
Background. Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal haematopoietic stem cell disorder characterised by intravascular haemolysis, bone marrow failure and increased tendency to thrombosis.
Uroš Mlakar, Darja Žontar
doaj
Hemoglobinuria paroxística nocturna: Actualización Paroxysmal nocturnal haemoglobinuria
La hemoglobinuria paroxística nocturna (HPN) es una enfermedad clonal y adquirida causada por una mutación somática en el gen PIG-A que se encuentra en el cromosoma X y codifica una proteina involucrada en la síntesis del glicosilfosfatidilinositol (GPI),
María Teresa Milanés Roldán +4 more
doaj
Is Allogeneic Stem Cell Transplantation a Good Option for Paroxysmal Nocturnal Haemoglobinuria?
Fatma Keklik Karadağ +2 more
doaj +1 more source
Safety of Crovalimab Versus Eculizumab in Patients With Paroxysmal Nocturnal Haemoglobinuria (PNH): Pooled Results From the Phase 3 COMMODORE Studies. [PDF]
Röth A +17 more
europepmc +1 more source
Editorial: Biological aspects of bone marrow failure
Panagiotis Diamantopoulos +2 more
doaj +1 more source
Aplastic anaemia with small paroxysmal nocturnal haemoglobinuria clones developing during osimertinib therapy for non-small cell lung cancer. [PDF]
Morimoto H +9 more
europepmc +1 more source
A case report of CD4<sup>-</sup> CD8<sup>+</sup> CD56<sup>-</sup> TCRγδ<sup>+</sup> T-large granular lymphocytic leukaemia with severe aplastic anemia and a PNH clone. [PDF]
Du Y, Zhang J, Jin S.
europepmc +1 more source
FACIT-fatigue score and treatment quality assessment for paroxysmal nocturnal hemoglobinuria patients treated with Eculizumab in Türkiye. [PDF]
Narlı Özdemir Z +33 more
europepmc +1 more source

